Hemorrhoid Suppositories, Creams & Wipes
Preparation H, Anusol, Calmol 4, NeilMed, Tucks, Doctor Butler's, Calmoseptine, Boiron HemCalm, sitz bath salts, and the pregnancy and postpartum picks.
Start with the top guides
Buyer's Guide
Best Hemorrhoid Suppositories (2026): Preparation H, Anusol, Calmol 4 and NeilMed Ranked
Buy Preparation H Hemorrhoid Suppositories, 12 count, pack of 2, at $17.96. It is the reference internal hemorrhoid suppository, its Drug Facts label lists a vasoconstrictor and a protectant, and the two-pack works out to about 75 cents per suppository. Below it: Anusol, Calmol 4 with cocoa butter and zinc oxide, NeilMed, and the hyaluronic acid and witch hazel alternatives for people who want something other than the standard formula. Prices verified via the Amazon Creators API on September 5, 2026.
Read the guide~14 min read
Buyer's Guide
The Best Hemorrhoid Creams and Ointments (2026): Preparation H, Doctor Butler's, Curist, Boiron
Buy Preparation H Hemorrhoid Symptom Treatment Cream, 2 oz, at $12.48. It is the reference external cream, its Drug Facts panel pairs phenylephrine with protectants, and the 2 oz tube is about $6.24 an ounce against $8.64 for the 0.9 oz. Below it: the petrolatum ointment, the lidocaine creams from Preparation H, Doctor Butler's and Curist, the store-brand ointment, the homeopathic Boiron, and Calmoseptine for the skin around the problem. Prices verified via the Amazon Creators API on September 5, 2026.
Read the guide
Buyer's Guide
Hemorrhoid Wipes, Ranked (2026): Preparation H, DUDE Wipes, Tucks and Doctor Butler's
Buy Preparation H Hemorrhoid Wipes with Witch Hazel, 48 count, at $6.34. It is the reference medicated wipe, witch hazel is the labeled active, and 48 for $6.34 is about 13 cents a wipe. Below it: the 96 count, DUDE Wipes at 144 for about 14 cents, Tucks pads at 8 cents, the Totables travel pack, Doctor Butler's organic witch hazel wipes, and the Rapid Relief lidocaine wipe for pain. Prices verified via the Amazon Creators API on September 5, 2026.
Read the guide
Buyer's Guide
Which Witch Hazel Pads Should You Buy? Tucks, Preparation H, Birchwood A-E-R and Major Medi-Pads (2026)
Buy Tucks Medicated Cooling Pads, 100 count, at $7.68. It is the witch hazel pad every other pad is compared against, the Drug Facts label covers external itching, burning and irritation, and 100 for $7.68 is about 8 cents a pad, the cheapest per use on the shelf. Below it: the Tucks kit with cream, Preparation H's wipe, Birchwood's A-E-R pads titled for postpartum, the Major Medi-Pads jar with aloe, and DUDE's big box. Prices verified via the Amazon Creators API on September 5, 2026.
Read the guide
How we rank
We rank every product on the things that decide a good buy: verified active ingredient and strength, count and cost per dose, and the label's own directions and safety lines. We cross-check the Drug Facts or Supplement Facts panel and live listing against the consistent testimony of real owners, and we say plainly whose number each figure is. No brand pays for a spot.
Everything in Hemorrhoid Suppositories, Creams & Wipes
- Hemorrhoid Relief in Pregnancy and Postpartum (2026): Tucks, Sitz Salts, Perineal Spray and the BarrierBuyer's Guide
Best Sitz Bath Salts (2026): Lansinoh, and What to Pair With the SoakBuyer's Guide
Best Lidocaine Hemorrhoid Creams (2026): Preparation H, Doctor Butler's and Curist ComparedBuyer's Guide
Anal Fissure Treatments You Can Buy OTC (2026): Doctor Butler's, Curist, PROKTIS-M and the CleansersBuyer's Guide- Preparation H Suppositories Review: The Phenylephrine Suppository, Box by BoxReview
Anusol Suppositories Review: The Other Pharmacy Name, and What the Listing Does Not Tell YouReview
Calmol 4 Review: The Protectant-Only Hemorrhoid Suppository Without PhenylephrineReview- Tucks Pads Review: The Witch Hazel Pad, and Whether the Kit or the Wipes Beat ItReview
- Doctor Butler's Review: The Lidocaine and Phenylephrine Ointment, and the Rest of the LineReview
Boiron HemCalm Review: A Homeopathic Ointment and Tablet, Explained Without the MarketingReview
Calmoseptine Review: The Barrier Ointment People Use Around Hemorrhoids, and What Its Label Actually SaysReview
Proktis-M Review: The Hyaluronic Acid Rectal Suppository, Without the ClaimsReview- Preparation H vs Anusol Suppositories: Printed Panel Against Pharmacy NameComparison
- Preparation H vs Calmol 4: Vasoconstrictor or Protectant Only?Comparison
- Suppository vs Cream for Hemorrhoids: Which Preparation H Format to Use, and WhenComparison
- Tucks vs Preparation H Wipes: Pad or Wipe, and the Moment Each One Is ForComparison
Ranked on real heat
Not sure which one fits your situation? See our top picks.
Every major pick ranked, with the reasoning shown and a direct link to buy.
More collections
Suppositories 101
Start here: what a suppository is, how to insert one, how long each type takes, storage, applicators, and suppository vs enema vs oral.
Constipation Suppositories, Enemas & Laxatives
Glycerin and bisacodyl suppositories, liquid glycerin, saline and mineral oil enemas, and the stool softeners and oral laxatives beside them: Fleet, Pedia-Lax, Dulcolax, NeilMed, MiraLAX, Colace.
Vaginal Suppositories & Moisturizers
Boric acid, probiotic, vitamin E, tea tree and hyaluronic acid suppositories, vaginal moisturizers, OTC antifungals, pH strips and applicators: pH-D, Love Wellness, AZO, Monistat, Bonafide Revaree, Replens, Carlson.
Fever & Pain Suppositories
Acetaminophen suppositories for infants, children and juniors: FeverAll strengths, the label's weight-and-age directions, and when a suppository beats oral.
Babies & Kids
Constipation, gas and fever relief made for small bodies: Pedia-Lax, Windi, infant glycerin, kids enemas, probiotic drops, FeverAll, with the label age cut-offs on every page.
Head-to-Head Comparisons
The matchups readers search: glycerin vs bisacodyl, Dulcolax vs Fleet, suppository vs enema, Preparation H vs Anusol, pH-D vs Love Wellness, Monistat 1 vs 3 vs 7.