Suppositories 101

Start here: what a suppository is, how to insert one, how long each type takes, storage, applicators, and suppository vs enema vs oral.

16 guidesRanked on verified label facts$0 paid placementsUpdated September 2026

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How we rank

We rank every product on the things that decide a good buy: verified active ingredient and strength, count and cost per dose, and the label's own directions and safety lines. We cross-check the Drug Facts or Supplement Facts panel and live listing against the consistent testimony of real owners, and we say plainly whose number each figure is. No brand pays for a spot.

Our methodology →

Ranked on real heat

Not sure which one fits your situation? See our top picks.

Every major pick ranked, with the reasoning shown and a direct link to buy.

Our top picks →

Our top-rated suppositories

Whatever you decide, these are the picks we recommend across every shelf, ranked on verified label facts and cost per dose. Live price check on each.

Fleet Glycerin, Adult 50 ct

Best Overall

Fleet Glycerin, Adult 50 ct

glycerin · 50 ct · ~$4

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Dulcolax Bisacodyl 10 mg

Best Fast-Acting

Dulcolax Bisacodyl 10 mg

bisacodyl · 4 ct · ~$5

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Preparation H Suppositories

Best for Hemorrhoids

Preparation H Suppositories

12 ct x 2 · ~$18

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pH-D Boric Acid 600 mg

Best Boric Acid

pH-D Boric Acid 600 mg

600 mg · 24 ct · ~$27

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Pedia-Lax Liquid Glycerin, Kids

Best for Kids

Pedia-Lax Liquid Glycerin, Kids

ages 2 to 5 · 6 ct x 3 · ~$21

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FeverAll Infant 80 mg

Best Fever

FeverAll Infant 80 mg

acetaminophen · 6 ct · ~$13

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