Our Pick: Fleet
Check price on Amazon →Best Suppositories for Constipation (2026): Glycerin, Bisacodyl and Kids Picks
Buy Fleet Glycerin Suppositories, 50 count, at $4.29. It is the adult glycerin suppository the whole shelf is measured against, its Drug Facts label says it generally produces a bowel movement in 15 minutes to 1 hour, and it costs about 9 cents a dose. Below it: the liquid glycerin applicator, the bisacodyl stimulant picks for when glycerin is not enough, and the two kids products the labels actually cover. Prices verified via the Amazon Creators API on September 5, 2026.
By The Pharmacy Desk2026-09-05~14 min read Ranked on verified label facts, never box claimsHow we research
Buy Fleet Glycerin Suppositories, 50 count, at $4.29 (verified via the Amazon Creators API on September 5, 2026). For an adult with occasional constipation who wants relief in under an hour without a stimulant, this is the answer: 2 g of glycerin per suppository, a label that reads 15 minutes to 1 hour, and a cost per dose of about 9 cents ($4.29 divided by 50). If glycerin has not done it for you, the stimulant answer is the Dulcolax Medicated Suppository, bisacodyl 10 mg, at $5.48 for 4. For a child aged 2 to 5, the label-covered pick is Pedia-Lax Liquid Glycerin Suppositories at $12.81 for 6.
A rectal suppository is the fastest over-the-counter route to a bowel movement short of an enema, and the shelf splits cleanly in two. Glycerin suppositories are hyperosmotic: they draw water into the lower bowel and soften what is there, and every glycerin label on this page says the same 15 minutes to 1 hour. Bisacodyl suppositories are stimulant laxatives: they act on the bowel wall itself, carry the same 15 minutes to 1 hour on the label, and the label is explicit that they are for occasional use. Liquid glycerin is glycerin in a pre-filled applicator, for people who find a solid suppository awkward. The kids products are the same actives at pediatric sizes with their own age lines. None of this is subtle, which is why the page ranks on what is printed: active ingredient, strength where the listing states it, count, cost per dose, and the ages the label covers.
One paragraph of rules before the ranking, because every product here is an OTC drug with a Drug Facts panel. Laxatives, suppository or otherwise, are labeled for occasional constipation. The labels say to ask a doctor before use if you have stomach pain, nausea or vomiting, or a sudden change in bowel habits lasting over 2 weeks; to stop and ask a doctor if you have rectal bleeding or fail to have a bowel movement after use, because those can be signs of a serious condition; and not to use a laxative for more than 1 week unless a doctor tells you to. For a child, the pediatrician decides. We read labels and verify listings; we are not clinicians, nothing here is medical advice, and no brand has paid for a placement. If you buy through a link we may earn an Amazon commission at no cost to you.
The short version
- Our Pick: Fleet Glycerin Suppositories, 50 count, $4.29 at our September 5, 2026 check. Adult glycerin 2 g, label time 15 minutes to 1 hour, about 9 cents a dose.
- If you want a stimulant: Dulcolax Medicated Suppositories, bisacodyl 10 mg, $5.48 for 4. Same 15 minutes to 1 hour on the label, but a stimulant laxative, for occasional use.
- Prefer a liquid: Fleet Liquid Glycerin Suppositories, 4 pre-filled applicators for $5.58, about $1.40 each, the only glycerin format that needs no handling of a solid.
- For a child aged 2 to 5: Pedia-Lax Liquid Glycerin Suppositories, 6 for $12.81. The label covers ages 2 to 5 and says ask a doctor under 2.
- Every laxative label on this page carries the same three stop lines: rectal bleeding, no bowel movement after use, and use beyond 1 week all mean ask a doctor.
At a glance
| Product | Active | Label ages | Count | Cost per dose | Price (9/5/26) | Check price |
|---|---|---|---|---|---|---|
| Fleet Glycerin Suppositories, 50 ct | Glycerin 2 g | 6 and over; under 6 ask a doctor | 50 | $0.09 | $4.29 | Check price on Amazon |
| NeilMed Glycerin Suppositories | Glycerin | Per label | 30 | $0.31 | $9.19 | Check price on Amazon |
| Rising Proctozone-GMax Adult 2 g | Glycerin 2 g | Adult, per label | Not published | n/a | $12.99 | Check price on Amazon |
| Fleet Liquid Glycerin, 4 applicators | Glycerin (liquid) | 6 and over; under 6 ask a doctor | 4 | $1.40 | $5.58 | Check price on Amazon |
| Dulcolax Medicated Suppositories, 4 ct | Bisacodyl 10 mg | 12 and over; 6 to under 12 per label; under 6 ask a doctor | 4 | $1.37 | $5.48 | Check price on Amazon |
| Major Bisacodyl 10 mg, 12 ct | Bisacodyl 10 mg | Per label | 12 | $0.83 | $9.99 | Check price on Amazon |
| Pedia-Lax Liquid Glycerin, 6 ct | Glycerin (liquid), pediatric | 2 to 5; under 2 ask a doctor | 6 | $2.14 | $12.81 | Check price on Amazon |
| Rising Health Children's Glycerin 1.2 g | Glycerin 1.2 g | 2 to 5 per title | Not published | n/a | $9.99 | Check price on Amazon |
The eight suppositories on this page. Active ingredients and strengths are as stated on the Amazon listing title or the Drug Facts label; where the title states no count, we say so. Prices are live Amazon figures verified via the Creators API on September 5, 2026. Cost per dose is computed only where the listing states both price and count.
Fleet Glycerin Suppositories, 50 count
Fleet
The reference adult glycerin suppository: 2 g, 15 minutes to 1 hour, about 9 cents a dose.
Our verdict: This is the suppository every other product on this page is compared against, and at $4.29 for 50 it is also the cheapest per dose. The label is the whole argument: 2 g glycerin, occasional constipation, 15 minutes to 1 hour, ages 6 and over with under 6 sent to a doctor. Buy it first; move down the page only if it has not worked for you.
Verified: Labeled active: glycerin 2 g per adult suppository, 50 per jar. Drug Facts label: for relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Live at $4.29 on Amazon, verified via the Creators API on September 5, 2026.
The plain adult glycerin suppository, from the brand that defines it. The Fleet Glycerin Suppositories, 50 count jar is what a pharmacist reaches for when an adult asks for something faster than a pill and gentler than a stimulant. The Drug Facts label states glycerin 2 g per suppository, lists the use as relief of occasional constipation, and says it generally produces a bowel movement in 15 minutes to 1 hour. Directions on the label: adults and children 6 years and over, 1 suppository once daily or as directed by a doctor; children under 6, ask a doctor.
What the label says to watch: ask a doctor before use if you have stomach pain, nausea or vomiting, or a sudden change in bowel habits that lasts over 2 weeks. Stop use and ask a doctor if you have rectal bleeding or fail to have a bowel movement after use, and do not use a laxative for more than 1 week unless directed by a doctor. Owners consistently report the jar suppositories can arrive soft in summer; the fix on the label is to chill them before unwrapping. Full write-up in our Fleet Glycerin Suppositories review; the wider field is in the best glycerin suppositories, and the timing question is answered in how long a glycerin suppository takes to work.
Who should buy it
Buy the 50 count jar if you are an adult with occasional constipation who wants relief within the hour without a stimulant, and you would rather keep a jar in the cabinet than buy a 4 pack every time. It is the correct first purchase on this entire shelf.
What we don't like
Jar packaging means the suppositories are loose rather than individually wrapped, and owners report they soften in a warm bathroom. The label does not cover children under 6 at all.
- Active ingredient
- Glycerin
- Strength
- 2 g per suppository (adult, per label)
- Count
- 50
- Form
- Solid rectal suppository, jar
- Label ages
- 6 years and over; under 6 ask a doctor
- Cost per dose
- $0.09 ($4.29 divided by 50)
- Packaging
- Jar, not individually wrapped
What we like
- Cheapest cost per dose on the page at about 9 cents
- Label time of 15 minutes to 1 hour, no stimulant
- Adult 2 g strength from the reference brand
- 50 per jar is a year of occasional use for most households
Worth noting
- Loose in a jar, not individually wrapped
- Can soften in a warm bathroom
- Label does not cover children under 6
NeilMed Glycerin Laxative Suppositories, 30 count
NeilMed
Glycerin suppositories individually wrapped, for a travel bag or a shared cabinet.
Our verdict: NeilMed's glycerin suppository exists for one reason Fleet's jar does not solve: each one is individually wrapped. That costs about 31 cents a dose against Fleet's 9, and for a travel bag, a shared bathroom, or a warm climate where loose suppositories soften, it is worth the difference. Same active, same label use.
Verified: Labeled active: glycerin (strength per suppository not stated on the listing title). Individually wrapped, 30 per box per the listing title. Drug Facts label: for relief of occasional constipation. Live at $9.19 on Amazon, verified via the Creators API on September 5, 2026.
The wrapped alternative. The NeilMed Glycerin Laxative Suppositories put the same active as Fleet, glycerin, in individually wrapped units, 30 to the box per the listing title. The label use is relief of occasional constipation, and like every glycerin suppository it is hyperosmotic. NeilMed is best known for saline rinses, and its laxative line brings the same packaging discipline: a wrapper per unit, a sealed box, and a listing that states the count.
The listing title does not state the glycerin amount per suppository; the Drug Facts panel on the box does, so read it rather than assuming it matches Fleet's 2 g. The same label lines apply: stop and ask a doctor for rectal bleeding or no bowel movement after use, and no laxative beyond 1 week without a doctor. The full brand write-up is our NeilMed suppositories review.
Who should buy it
Buy NeilMed if you want glycerin suppositories that are individually wrapped, either because they travel with you or because a loose jar in a warm bathroom has softened on you before.
What we don't like
About 31 cents a dose against Fleet's 9, and the listing title does not state the glycerin amount per suppository, so you have to read the box for the strength.
- Active ingredient
- Glycerin
- Strength
- Not stated on the listing title; on the Drug Facts panel
- Count
- 30 (per listing title)
- Form
- Solid rectal suppository, individually wrapped
- Label ages
- Per the Drug Facts panel
- Cost per dose
- $0.31 ($9.19 divided by 30)
- Packaging
- Individually wrapped, boxed
What we like
- Individually wrapped, the main thing Fleet's jar lacks
- Count stated on the listing (30)
- Same active and same label use as the pick
Worth noting
- Roughly three times Fleet's cost per dose
- Strength not stated on the listing title
Rising Proctozone-GMax Adult Glycerin Suppositories, 2 g
Rising Health
A pharmacy-brand adult 2 g glycerin suppository with the strength printed in the title.
Our verdict: Rising Health is a pharmacy-shelf generic house, and the Proctozone-GMax is its adult glycerin suppository at the same 2 g Fleet uses, with the strength printed right in the listing title. The listing does not state the count, so we cannot compute a cost per dose, which is the honest reason it ranks below the two products above it.
Verified: Labeled active: glycerin 2 g per adult suppository, stated in the listing title. Labeled for fast relief of occasional constipation. Count not stated on the listing title. Live at $12.99 on Amazon, verified via the Creators API on September 5, 2026.
Same strength, different house. The Rising Proctozone-GMax Adult Glycerin Suppositories state 2 g glycerin per suppository in the listing title, which is the adult strength the category runs on, and the title labels them a rectal laxative for fast relief of occasional constipation. Rising Health is a generic pharmaceutical brand rather than a consumer name, which is why you may not recognize it and why the price sits where it does.
The Drug Facts lines are the standard glycerin set: ask a doctor before use for stomach pain, nausea, vomiting or a sudden change in bowel habits over 2 weeks; stop and ask a doctor for rectal bleeding or no bowel movement after use; not more than 1 week without a doctor. For the adult-only field with every count and price side by side, see the best glycerin suppositories for adults.
Who should buy it
Consider the Proctozone-GMax if you specifically want a pharmacy-generic adult 2 g glycerin suppository and Fleet or NeilMed is out of stock or unavailable to you.
What we don't like
The count is not stated on the listing title, so there is no cost per dose to compare, and at $12.99 it is priced above the reference jar.
- Active ingredient
- Glycerin
- Strength
- 2 g per suppository (per listing title)
- Count
- Not published on the listing title
- Form
- Solid rectal suppository
- Label ages
- Adult, per the Drug Facts panel
- Packaging
- Boxed
What we like
- 2 g adult strength stated in the title
- Pharmacy-generic house with a clear laxative label
- A second source when the big brands are out
Worth noting
- Count not published, so no cost per dose
- Priced above the Fleet jar
Fleet Liquid Glycerin Suppositories, 4 applicators
Fleet
Glycerin in a pre-filled applicator, no solid to handle, same label window.
Our verdict: Liquid glycerin solves the one complaint people have about a solid suppository, which is the suppository. Each applicator is pre-filled, used once and thrown away, and the label carries the same 15 minutes to 1 hour as the solid. At about $1.40 per use it is fifteen times Fleet's jar price per dose, and for the people who need it, that is fine.
Verified: Labeled active: glycerin, liquid, in a single-use pre-filled applicator, 4 per box. Drug Facts label: for relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Live at $5.58 on Amazon, verified via the Creators API on September 5, 2026.
The format for people who will not use a solid. Fleet Liquid Glycerin Suppositories are glycerin in a small pre-filled applicator with a tip that is inserted, squeezed and discarded. Nothing has to be unwrapped, warmed, or held. The Drug Facts label reads relief of occasional constipation and generally produces a bowel movement in 15 minutes to 1 hour, the same window as the solid suppository, and the directions are for adults and children 6 years and over, with under 6 sent to a doctor.
The listing title does not state the glycerin amount per applicator; the Drug Facts panel does. Same stop lines as every laxative here: rectal bleeding, no bowel movement after use, more than 1 week, all mean ask a doctor. The full format comparison is in the best liquid glycerin suppositories.
Who should buy it
Buy the liquid if the solid suppository is the reason you have been avoiding this shelf, or if you are helping someone else and want the simplest possible single-use format.
What we don't like
About $1.40 per use against 9 cents for the jar, and the listing title does not state the glycerin amount per applicator.
- Active ingredient
- Glycerin (liquid)
- Strength
- Not stated on the listing title; on the Drug Facts panel
- Count
- 4 single-use applicators
- Form
- Pre-filled rectal applicator
- Label ages
- 6 years and over; under 6 ask a doctor
- Cost per dose
- $1.40 ($5.58 divided by 4)
- Packaging
- Boxed, each applicator sealed
What we like
- No solid suppository to handle or warm
- Same 15 minutes to 1 hour window on the label as the solid
- Single-use, sealed, easy to carry
Worth noting
- About fifteen times the jar's cost per dose
- Only 4 per box
- Amount per applicator not stated on the listing
Dulcolax Stimulant Laxative Medicated Suppositories, 4 count
Dulcolax
The reference bisacodyl 10 mg suppository, for when glycerin is not enough.
Our verdict: When a glycerin suppository has not produced a bowel movement, the next step the pharmacy shelf offers is bisacodyl, and Dulcolax is the brand that defines it. Ten milligrams, 15 minutes to 1 hour on the label, and a clear line that this is a stimulant for occasional use. The 4 count at $5.48 is the right size for something you should not be using routinely.
Verified: Labeled active: bisacodyl 10 mg per suppository, stimulant laxative, 4 per box. Drug Facts label: for relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Live at $5.48 on Amazon, verified via the Creators API on September 5, 2026.
The stimulant, sized for occasional use. Dulcolax Stimulant Laxative Medicated Suppositories contain bisacodyl 10 mg per suppository. Where glycerin draws water in, bisacodyl acts on the bowel wall directly, which is why the label calls it a stimulant laxative and why we put it below glycerin rather than beside it. The Drug Facts label reads relief of occasional constipation and generally produces a bowel movement in 15 minutes to 1 hour. Directions: adults and children 12 years and over, 1 suppository in a single daily dose; children 6 to under 12 years have a separate reduced direction printed on the label; children under 6, ask a doctor.
The label's own caution list for bisacodyl includes the standard laxative lines, rectal bleeding, no bowel movement after use, and not more than 1 week without a doctor, plus abdominal discomfort, faintness and cramps as possible effects. Read the box you buy; the suppository label carries its own warnings. The head-to-head is in glycerin vs bisacodyl suppositories and the brand deep dive is the Dulcolax suppositories review.
Who should buy it
Buy the Dulcolax 4 count if glycerin has not worked for you and you want the reference stimulant suppository in a box sized for the occasional use the label describes.
What we don't like
It is a stimulant, with cramping and discomfort listed as possible effects, and at about $1.37 a dose it is far above glycerin. The under 6 line is ask a doctor, not a direction.
- Active ingredient
- Bisacodyl
- Strength
- 10 mg per suppository
- Count
- 4
- Form
- Solid rectal suppository, individually sealed
- Label ages
- 12 and over; 6 to under 12 per label; under 6 ask a doctor
- Cost per dose
- $1.37 ($5.48 divided by 4)
- Packaging
- Boxed, sealed
What we like
- Reference bisacodyl 10 mg from the category brand
- 15 minutes to 1 hour on the label
- Box of 4 fits the occasional-use label
Worth noting
- Stimulant; cramps and discomfort are listed possible effects
- About $1.37 per dose
- Ask a doctor under 6
Major Bisacodyl 10 mg Suppositories, 12 count
Major Pharmaceuticals
Pharmacy-generic bisacodyl 10 mg at about 83 cents a dose, 12 comfort-shaped units.
Our verdict: Major is the generic house behind a great deal of what sits on hospital and pharmacy shelves, and its bisacodyl suppository is the same 10 mg as Dulcolax at about 83 cents a dose instead of $1.37. The 12 count is still within occasional-use territory. If you have used bisacodyl before and know it is what you need, this is the value buy.
Verified: Labeled active: bisacodyl 10 mg per suppository, stimulant laxative, 12 comfort-shaped per the listing title. Labeled for occasional constipation. Live at $9.99 on Amazon, verified via the Creators API on September 5, 2026.
Same active, generic label, lower price per dose. Major Bisacodyl 10 mg Suppositories come 12 to the box, comfort-shaped per the listing title, and the label describes them as a stimulant laxative for gentle, predictable, fast relief. The strength is the category standard 10 mg, the same as Dulcolax. At $9.99 (verified via the Amazon Creators API on September 5, 2026) that is about 83 cents a dose ($9.99 divided by 12).
Directions and warnings are the bisacodyl set: single daily dose, separate reduced direction for children 6 to under 12, ask a doctor under 6, stop and ask a doctor for rectal bleeding or no bowel movement after use, and not more than 1 week without a doctor. The full bisacodyl field, including Paddock and NeilMed, is ranked in the best bisacodyl suppositories.
Who should buy it
Buy Major if you already know bisacodyl is the right suppository for you and you want the lowest verified cost per dose at the standard 10 mg strength.
What we don't like
A generic box with no consumer-brand support, and 12 stimulant suppositories is more than a genuinely occasional user will get through before checking the expiry.
- Active ingredient
- Bisacodyl
- Strength
- 10 mg per suppository
- Count
- 12
- Form
- Solid rectal suppository, comfort-shaped
- Label ages
- Per the Drug Facts panel (bisacodyl standard: 12 and over; 6 to under 12 per label; under 6 ask a doctor)
- Cost per dose
- $0.83 ($9.99 divided by 12)
- Packaging
- Boxed
What we like
- Standard 10 mg bisacodyl at about 83 cents a dose
- 12 count, comfort-shaped per the title
- Generic house that supplies pharmacies
Worth noting
- Still a stimulant, still occasional use only
- No consumer brand behind the box
Pedia-Lax Liquid Glycerin Suppositories, 6 count
Pedia-Lax (Fleet)
The pediatric liquid glycerin applicator, labeled for ages 2 to 5, ask a doctor under 2.
Our verdict: For a constipated child between 2 and 5, Pedia-Lax Liquid Glycerin is the product whose label actually covers the age, in the format that is easiest to use on a child who is not cooperating. Six applicators for $12.81 is about $2.14 each. The label says ask a doctor under 2, and on this shelf, the pediatrician decides regardless.
Verified: Labeled active: glycerin, liquid, pediatric pre-filled applicator, 6 per box. Drug Facts label: for relief of occasional constipation in children ages 2 to 5; under 2 years, ask a doctor. Live at $12.81 on Amazon, verified via the Creators API on September 5, 2026.
The kids product with the clearest label. Pedia-Lax Liquid Glycerin Suppositories are Fleet's pediatric line: glycerin in a small pre-filled applicator sized for a child, 6 per box, labeled for relief of occasional constipation in children ages 2 to 5. The label's direction for under 2 years is ask a doctor. That single age line is the reason this product, and not a cut-down adult suppository, is the pick for a young child.
Owners consistently report the applicator is easier on a wriggling child than a solid suppository, which is the practical case for the liquid format at this age. The brand review is our Pedia-Lax review, the kids field is ranked in the best glycerin suppositories for kids, and the adult-versus-pediatric question is settled in Fleet vs Pedia-Lax.
Who should buy it
Buy Pedia-Lax Liquid Glycerin for a child aged 2 to 5 with occasional constipation, once the pediatrician has said a glycerin suppository is appropriate, and you want the format that is easiest to use.
What we don't like
About $2.14 per use in the 6 count, and the label stops at age 5 on one end and sends everyone under 2 to a doctor on the other, which is exactly how it should be, but it means most households will only ever buy one box.
- Active ingredient
- Glycerin (liquid), pediatric
- Strength
- Not stated on the listing title; on the Drug Facts panel
- Count
- 6 single-use applicators
- Form
- Pediatric pre-filled rectal applicator
- Label ages
- 2 to 5 years; under 2 ask a doctor
- Cost per dose
- $2.14 ($12.81 divided by 6)
- Packaging
- Boxed, each applicator sealed
What we like
- Label explicitly covers ages 2 to 5
- Pre-filled applicator, easiest format for a young child
- From the same house as the adult reference product
Worth noting
- About $2.14 per use
- Ask a doctor under 2; not covered above 5
Rising Health Children's Glycerin Suppositories, 1.2 g
Rising Health
A pediatric-strength solid glycerin suppository, 1.2 g, titled for ages 2 to 5.
Our verdict: If the pediatrician has said a solid glycerin suppository is fine and you would rather have a pediatric size than cut an adult one, the Rising Health Children's 1.2 g is the product with the strength and the age range printed in its title. The count is not published, so no cost per dose. It is the solid counterpart to Pedia-Lax's liquid.
Verified: Labeled active: glycerin 1.2 g per pediatric suppository, stated in the listing title, which also states ages 2 to 5. Rectal laxative for kids. Count not stated on the listing title. Live at $9.99 on Amazon, verified via the Creators API on September 5, 2026.
A pediatric strength, not a cut-down adult. The Rising Health Children's Glycerin Suppositories state 1.2 g glycerin per suppository in the listing title, along with the age range, kids 2 to 5 years, and the use, a rectal laxative for fast relief of occasional constipation. That is a purpose-made pediatric size. The adult suppository is 2 g; the pediatric category runs roughly 1 to 1.2 g, and this one prints the number.
Directions and stop lines are the pediatric glycerin set: ages 2 to 5 on the title, ask a doctor under 2 on the label, stop and ask a doctor for rectal bleeding or no bowel movement after use. And the standing rule for every child: the pediatrician decides. If you are choosing for a baby rather than a toddler, the age lines are different and the products are different; read the best glycerin suppositories for infants and suppositories for babies and toddlers before buying anything.
Who should buy it
Buy the Rising Health Children's 1.2 g if a pediatrician has approved a glycerin suppository for your 2 to 5 year old and you prefer a solid pediatric size over the liquid applicator.
What we don't like
The count is not published on the listing, so there is no cost per dose, and Rising Health is a generic house with none of the consumer-facing support Pedia-Lax has.
- Active ingredient
- Glycerin
- Strength
- 1.2 g per suppository (per listing title)
- Count
- Not published on the listing title
- Form
- Solid pediatric rectal suppository
- Label ages
- 2 to 5 years (per title); under 2 ask a doctor
- Packaging
- Boxed
What we like
- Pediatric 1.2 g strength printed in the title
- Age range 2 to 5 printed in the title
- Solid alternative to the liquid applicator
Worth noting
- Count not published, no cost per dose
- Generic house, limited consumer support
More picks worth comparing
Beyond this guide, the highest-rated picks across every category and budget, with a live price check on each.
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Quick shop: every pick
Skip the scroll: the whole lineup, with a live price check on each.
- Fleet Glycerin Suppositories, 50 countBest OverallFleet · $4.29Check price on Amazon
- NeilMed Glycerin Laxative Suppositories, 30 countBest Individually Wrapped GlycerinNeilMed · $9.19Check price on Amazon
- Rising Proctozone-GMax Adult Glycerin Suppositories, 2 gBest Value Brand Adult 2 gRising Health · $12.99Check price on Amazon
- Fleet Liquid Glycerin Suppositories, 4 applicatorsBest Liquid GlycerinFleet · $5.58Check price on Amazon
- Dulcolax Stimulant Laxative Medicated Suppositories, 4 countBest Bisacodyl (Stimulant)Dulcolax · $5.48Check price on Amazon
- Major Bisacodyl 10 mg Suppositories, 12 countBest Value BisacodylMajor Pharmaceuticals · $9.99Check price on Amazon
- Pedia-Lax Liquid Glycerin Suppositories, 6 countBest for Kids Ages 2 to 5Pedia-Lax (Fleet) · $12.81Check price on Amazon
- Rising Health Children's Glycerin Suppositories, 1.2 gBest Solid Kids Suppository, 1.2 gRising Health · $9.99Check price on Amazon
How we chose
Every product on this page is an over-the-counter drug with a Drug Facts panel, and the panel is what we rank on. For each listing we recorded the active ingredient and its strength where the title or label states it, the count, the form (solid suppository or pre-filled liquid applicator), the ages the label covers and the ages it sends to a doctor, and the price live on Amazon on September 5, 2026 via the Creators API. Cost per dose is shown only where the listing title gives both a price and a count, and we show the division. Where a listing title states no count or no strength, the table says not published rather than guessing. Owner reports were weighed for consistency on things a label cannot tell you: whether a suppository arrives melted, whether a wrapper tears cleanly, whether a jar seal holds.
Compliance for this shelf: we quote each label's Uses and Directions and nothing beyond them. We never suggest a dose the label does not print, we carry every age cut-off, and we repeat the stop lines every laxative label shares: rectal bleeding, no bowel movement after use, or use beyond 1 week mean stop and ask a doctor. Stimulant suppositories and enemas are for occasional use, not routine. For any child, the pediatrician decides which product and whether to use one at all. We are a research and verification desk, not a pharmacy or a clinic, and nothing on this page is medical advice. No brand paid for a placement and none saw the ranking before publication.
Questions, answered
What is the best suppository for constipation?
For an adult with occasional constipation, Fleet Glycerin Suppositories, 50 count, at $4.29 at our September 5, 2026 check. The Drug Facts label states glycerin 2 g, relief of occasional constipation, and a bowel movement generally within 15 minutes to 1 hour, and the jar works out to about 9 cents a dose. Glycerin is not a stimulant, which is why it is the first thing to try. If glycerin has not worked, the label says to ask a doctor; the stimulant alternative a doctor may be fine with is a bisacodyl 10 mg suppository such as Dulcolax.
How long does a glycerin suppository take to work?
The Drug Facts label on Fleet Glycerin Suppositories, and on every glycerin suppository we cover, states that it generally produces a bowel movement in 15 minutes to 1 hour. Liquid glycerin applicators carry the same window. Bisacodyl suppositories such as Dulcolax also state 15 minutes to 1 hour. If you have no bowel movement after use, the label's instruction is to stop and ask a doctor, because that can be a sign of a serious condition.
Glycerin or bisacodyl suppository: which should I use?
Glycerin first. It is hyperosmotic, meaning it draws water into the bowel and softens stool without stimulating the bowel wall, and its label window is 15 minutes to 1 hour. Bisacodyl is a stimulant laxative with the same label window but with cramps and abdominal discomfort listed as possible effects, and its label says occasional use only. Use bisacodyl only if glycerin has not worked and a doctor is fine with a stimulant. Both labels say not to use a laxative for more than 1 week unless a doctor directs.
Can I use a glycerin suppository every day?
Not without a doctor. Every laxative label on this page, glycerin and bisacodyl alike, says not to use laxatives for more than 1 week unless directed by a doctor, and the use listed is occasional constipation. If you find you need a suppository regularly, that is the label's own signal to talk to a clinician about why, rather than to keep buying jars.
Which suppository is safe for a child?
The pediatrician decides. What the labels state: Pedia-Lax Liquid Glycerin Suppositories are labeled for ages 2 to 5, and the Rising Health Children's Glycerin 1.2 g lists ages 2 to 5 in its title. Both say ask a doctor under 2. The adult Fleet glycerin label covers ages 6 and over and sends children under 6 to a doctor. Dulcolax bisacodyl covers 12 and over, has a separate reduced direction for 6 to under 12, and says ask a doctor under 6. No label on this page directs use in an infant, and neither do we.
Is a suppository better than an enema for constipation?
They are different tools. A glycerin suppository is labeled for a bowel movement in 15 minutes to 1 hour and is the less involved of the two. A saline enema is labeled for 1 to 5 minutes but requires holding a volume of liquid and carries its own warnings, including not using more than one in 24 hours. For most adults with occasional constipation the suppository is the first thing to try. Our suppository vs enema comparison covers the decision in full, and the best enemas guide ranks that shelf.
What if a suppository does not produce a bowel movement?
The label answers this directly: stop use and ask a doctor if you fail to have a bowel movement after using the product, or if you have rectal bleeding, because either could be a sign of a serious condition. Do not add a second suppository or move to a stimulant on your own. The same label lines appear on every glycerin and bisacodyl product we cover.
What do I do if the suppositories have melted?
Glycerin suppositories soften in heat, and the Fleet jar in particular arrives soft in warm months according to consistent owner reports. Cool them before use; refrigerating for a short time firms them up inside the wrapper or jar. Do not try to use a suppository that has lost its shape. Our guide on what to do when a suppository has melted covers storage and re-firming in detail.
Filed under Buyer's Guide
Keep reading
Best Glycerin Suppositories (2026)
Every glycerin format, adult, liquid, pediatric and infant, ranked on the label and the price.
Best Bisacodyl Suppositories (2026)
Dulcolax, Major, Paddock and NeilMed at 10 mg, ranked on cost per dose and the occasional-use label.
Glycerin vs Bisacodyl Suppositories
Hyperosmotic versus stimulant: the same label window, different mechanisms, and which to use first.
How to Insert a Suppository
The practical, plain-language walkthrough for rectal suppositories, solid and liquid.











