Best Lidocaine Hemorrhoid Creams (2026): Preparation H, Doctor Butler's and Curist Compared

The name brand's answer to pain. Preparation H Hemorrhoid Symptom Treatment Cream with Lidocaine, 1 oz states lidocaine in the title; the Drug Facts panel lists the full active set and percentages, which the listing does not. Lidocaine's Uses line is temporary relief of pain, itching and burning, and that is the reason to buy this tube over the standard Preparation H cream: when a bowel movement hurts and the hours after it hurt, numbing is the labeled answer. Directions are the hemorrhoidal standard: adults, apply up to 4 times daily, especially at night, in the morning and after each bowel movement; children under 12, ask a doctor.

Lidocaine's own lines: do not use in large quantities, particularly over raw surfaces or blistered areas; for external use only; stop and ask a doctor if the condition worsens or symptoms last more than 7 days. If the panel lists phenylephrine, its heart disease, high blood pressure, thyroid, diabetes and enlarged prostate ask-a-doctor conditions apply too. Bleeding means stop and ask a doctor; pregnant or breastfeeding means ask a health professional first. The non-lidocaine Preparation H tubes are ranked in the best hemorrhoid creams.

The tube with its numbers on the listing. Curist Fissure Hemorrhoid Cream states 5% lidocaine and phenylephrine in its title, along with 6 oz (170 g). Five percent is as much lidocaine as an OTC external product carries, and pairing it with phenylephrine gives the tube both the pain line and the swollen-tissue line on its Uses panel. The title also names fissures, which is why it is the second pick in the best anal fissure treatments. Directions: adults, up to 4 times daily; under 12, ask a doctor.

Both warning blocks apply and the volume makes them matter: lidocaine's do not use in large quantities, particularly over raw surfaces or blistered areas, and phenylephrine's ask a doctor before use for heart disease, high blood pressure, thyroid disease, diabetes, enlarged prostate, or a prescription for blood pressure or depression. Stop and ask a doctor for bleeding, worsening, or no improvement in 7 days; pregnant or breastfeeding, ask a health professional first.

The specialist's tube. Doctor Butler's Hemorrhoid & Fissure Ointment states lidocaine and phenylephrine HCl in the listing title and names fissures alongside hemorrhoids. The base is an ointment, which does not absorb the way a cream does and keeps a film on the skin through the next bowel movement, and that combination, an anesthetic that stays put, is why the brand has the following it does. Directions are the hemorrhoidal standard: adults up to 4 times daily; under 12, ask a doctor.

Both warning blocks apply: lidocaine's caution against large quantities and raw or blistered skin, and phenylephrine's ask-a-doctor conditions for heart disease, high blood pressure, thyroid disease, diabetes, enlarged prostate and prescription drugs for blood pressure or depression. Stop and ask a doctor for bleeding, worsening, or no improvement in 7 days; pregnant or breastfeeding, ask a health professional first. The whole line, including the spray and wipes without lidocaine, is covered in the Doctor Butler's review.

The step-up, with the change on the box. Doctor Butler's Advanced Hemorrhoid & Fissure Ointment states lidocaine in the title and describes itself as a lidocaine hemorrhoid treatment and fissure treatment. The title does not state phenylephrine the way the original's does, does not state the size, and does not say what Advanced means; the Drug Facts panel and the ingredient list answer all three, and the honest thing we can say is that the listing does not. At $29.99 (verified via the Amazon Creators API on September 5, 2026) it is $10 above the original and the most expensive Doctor Butler's tube.

Lidocaine's lines apply: not in large quantities, not over raw or blistered skin, stop and ask a doctor if worse or beyond 7 days. If the panel lists phenylephrine, its ask-a-doctor conditions apply too. Bleeding means stop and ask a doctor; pregnant or breastfeeding means ask a health professional first.

The travel format. Doctor Butler's Maximum Strength Hemorrhoid & Fissure Ointment, 12 to-go packets put the brand's ointment in single-use sachets, 12 to the box per the title. Each is one application: tear, apply, discard. The title says maximum strength and instant pain relief, and names hemorrhoids and fissures, but does not name the actives; the Drug Facts panel does, and the pain claim is the lidocaine use line. At $25.95 (verified via the Amazon Creators API on September 5, 2026) that is about $2.16 a packet ($25.95 divided by 12).

Lidocaine's lines apply: not in large quantities, not over raw or blistered skin, stop and ask a doctor if worse or beyond 7 days. If the panel lists phenylephrine, its ask-a-doctor conditions apply too. Bleeding means stop and ask a doctor; pregnant or breastfeeding means ask a health professional first.

Numbing, in the cleansing step. Preparation H Rapid Relief Hemorrhoid Wipes with Lidocaine state lidocaine in the title, and the title's use line runs to swelling, pain, burning and itching. Lidocaine's Drug Facts use is temporary relief of pain, itching and burning, and a wipe delivers it to the skin that hurts before anything else touches it. The witch hazel label's direction to cleanse before a topical treatment applies here too: wipe, then cream or ointment.

Lidocaine's lines: not in large quantities, not over raw or blistered skin, for external use only, stop and ask a doctor if worse or beyond 7 days. Under 12, ask a doctor; bleeding, stop and ask a doctor; pregnant or breastfeeding, ask a health professional first. The witch hazel wipes it replaces for people without pain are ranked in the best hemorrhoid wipes.