Best Acetaminophen Suppositories (2026): The FeverAll Strengths, Ranked

What the box states. FeverAll Infant Acetaminophen Suppositories are 80 mg of acetaminophen per rectal suppository, sold 6 to a box, labeled as a pain reliever and fever reducer. The Drug Facts panel prints the age the box is labeled for and the directions that go with it. Read that panel before the first use and follow it exactly; it is the only correct source for how many and how often, which is why no number of that kind appears on this page.

Practically, this is a product you buy in advance. Owners consistently describe the same scenario: a fever at 2 a.m., a toddler who has just vomited the grape syrup back up, and no way to get anything down. That is what the rectal route solves, and it is why the infant box belongs in the fridge next to the oral bottle rather than instead of it. If the child can keep oral medicine down, use oral first; our page on when to use a fever suppository walks through exactly where the line sits, and suppository vs oral acetaminophen compares the two routes head to head.

Two housekeeping notes. First, FeverAll also sells a paraben free infant version at $22.00 for parents who want that; its count is not published in the title, so we compute no cost per suppository for it. Second, store these cool. A soft suppository is hard to insert and easy to lose; see how to store suppositories and what to do when one melts.

The title problem, first, because it is the reason this card exists. The 120 mg FeverAll listing is titled with the word Infant on Amazon. FeverAll's own strength ladder puts 80 mg at infant, 120 mg at children's, and 325 mg at junior. So the word in the title and the strength in the box disagree, and the strength is the fact that matters. Buy the milligram number your pediatrician named.

At $15.09 for 6, this is about $2.52 per suppository, the most expensive single box on the page. The two-pack at $26.99 for 12 brings that down to about $2.25 each, which is one of the few multipacks here that genuinely saves money. As on every card: the box prints how many and how often, we do not. The strength-by-strength breakdown lives in acetaminophen suppository directions by age, and the direct comparison against the infant box is FeverAll infant vs children's.

Strength first. This FeverAll listing is 325 mg of acetaminophen per suppository, 6 to a box, at $9.40, which works out to about $1.57 each. It is the junior rung of the ladder. Amazon titles it with the word Children, which sits one rung below where 325 mg actually belongs, so this is the second listing on the page where the word and the number disagree.

Where this box is genuinely the right answer is an older child whose pediatrician named 325 mg and who cannot take anything by mouth. For everyone else it is the box to walk past. If you are trying to work out which rung applies, read the directions by age explainer first, and if the child can swallow, the honest answer is usually the oral bottle rather than any of these.

The math, since that is the entire argument for a multipack. The 120 mg two-pack is $26.99 for two boxes of 6, so 12 suppositories at about $2.25 each. The single 120 mg box is $15.09 for 6, about $2.52 each. Buying the pair saves roughly 27 cents per suppository, which is a real if modest saving on a product nobody uses in volume.

The same trick does not work at 80 mg. The infant two-pack is $29.50 for 12, about $2.46 each, against $2.12 each for the single box. On this shelf the multipack is sometimes the deal and sometimes the opposite, so do the division before you add to cart.

Do the division before you buy this one. The infant 80 mg two-pack is $29.50 for 12 suppositories, about $2.46 each. The single infant box is $12.73 for 6, about $2.12 each. Two singles at that price would be $25.46, so the multipack carries a premium rather than a discount at our September 5, 2026 check.

What it is genuinely good for is stocking two places at once with the infant strength, which is the strength a household with a baby actually wants on hand. If that convenience is worth about 34 cents per suppository to you, it is a reasonable buy. If it is not, order the single box twice.

What we can and cannot tell you. This listing is FeverAll acetaminophen suppositories sold as a pack of 4 at $35.74. The title does not print a milligram strength and does not print a total suppository count, so we print neither, and we compute no cost per suppository because there is nothing honest to divide by.

If you want four cartons, the safer route is four orders of a listing that names its strength, or two of the 120 mg two-pack. Check the current listing page and the Drug Facts panel photograph before committing to this one.

Start here, not with a suppository. GoodSense Children's Pain and Fever Oral Suspension is acetaminophen at 160 mg per 5 mL in a grape flavor, at $9.76. That concentration is the standard children's liquid strength, and the bottle comes with its own dosing device, which the Drug Facts panel tells you to use and only that one. The bottle volume is not published in the listing title, so we compute no cost per dose, but a bottle contains many doses and a 6 count suppository box contains six.

Two warnings the panel carries and this page will repeat anywhere it fits: never give two acetaminophen products at once, because a syrup and a suppository are the same drug and they add together, and measure only with the device that came in the box. As with everything here, the dose, the interval and the daily maximum are printed on the bottle and belong to the bottle.