Our Pick: Dulcolax
Check price on Amazon →Dulcolax Suppositories Review: The Reference Bisacodyl 10 mg, and Which Box to Buy
Buy the 4 count at $5.48. Bisacodyl 10 mg per suppository, a Drug Facts label that reads 15 minutes to 1 hour, and a box sized for the occasional use the same label insists on. The 28 count drops the cost per dose from about $1.37 to about 82 cents, but a stimulant laxative is not a product to stock. Major's generic 10 mg and Fleet's glycerin are the benchmarks. Prices verified via the Amazon Creators API on September 5, 2026.
By The Pharmacy Desk2026-09-05~11 min read Ranked on verified label facts, never box claimsHow we research
Upgrade PickDulcolax Fast Relief Medicated Laxative Suppositories, 10 mg, 28 count
Dulcolax · 4.3
$25.98
Buy Dulcolax Stimulant Laxative Medicated Suppositories, 4 count, at $5.48 (verified via the Amazon Creators API on September 5, 2026) if a doctor is fine with a stimulant suppository for occasional constipation. It is bisacodyl 10 mg, the strength the whole bisacodyl shelf runs on, from the brand that defines it, and its Drug Facts label states a bowel movement generally within 15 minutes to 1 hour. At about $1.37 per suppository ($5.48 divided by 4) it is not cheap per dose, and that is by design: the label says occasional use and not more than 1 week without a doctor, and a box of 4 matches that. If you have a standing reason to use more, the 28 count at $22.99 is about 82 cents each.
Dulcolax is the stimulant answer on the constipation shelf. Where a glycerin suppository is hyperosmotic and draws water into the lower bowel, bisacodyl acts on the bowel wall directly, which is why the label calls it a stimulant laxative and why we put it second, after glycerin, on every page of this site. Same window on the label, different mechanism, and a longer list of possible effects: the bisacodyl label names abdominal discomfort, faintness and cramps. This review covers every Dulcolax suppository listing on Amazon, explains why the 16 count is the one to skip, and benchmarks the brand against Major's generic bisacodyl and Fleet's glycerin.
The label governs, and we quote it. Bisacodyl suppositories are for relief of occasional constipation. Directions: adults and children 12 years and over, 1 suppository in a single daily dose; children 6 to under 12 years, a separate reduced direction printed on the label; children under 6, ask a doctor. Ask a doctor before use for stomach pain, nausea or vomiting, or a sudden change in bowel habits lasting over 2 weeks. Stop use and ask a doctor for rectal bleeding or no bowel movement after use. Do not use for more than 1 week unless a doctor directs. We read labels and verify listings; we are not clinicians, nothing here is medical advice, and no brand has paid for a placement. If you buy through a link we may earn an Amazon commission at no cost to you.
The short version
- Our Pick: Dulcolax Medicated Suppositories, 4 count, $5.48 at our September 5, 2026 check. Bisacodyl 10 mg, 15 minutes to 1 hour on the label, about $1.37 a dose, sized for occasional use.
- Lowest cost per dose in the line: the 28 count at $22.99, about 82 cents. Buy it only with a standing reason, because the label's 1 week line still applies.
- Skip the 16 count: at $24.49 it costs more than the 28 count for fewer suppositories, about $1.53 a dose.
- Generic benchmark: Major Bisacodyl 10 mg, 12 for $9.99, about 83 cents a dose, the same strength without the brand.
- Non-stimulant benchmark: Fleet Glycerin 50 count at $4.29, about 9 cents a dose, the product the label logic says to try first.
At a glance
| Product | Active | Count | Cost per dose | Label ages | Price (9/5/26) | Check price |
|---|---|---|---|---|---|---|
| Dulcolax Medicated Suppositories, 4 ct | Bisacodyl 10 mg | 4 | $1.37 | 12+; 6 to under 12 per label; under 6 ask a doctor | $5.48 | Check price on Amazon |
| Dulcolax Medicated Suppositories, 28 ct | Bisacodyl 10 mg | 28 | $0.82 | Same | $22.99 | Check price on Amazon |
| Dulcolax Fast Relief Suppositories, 28 ct | Bisacodyl 10 mg | 28 | $0.93 | Same | $25.98 | Check price on Amazon |
| Dulcolax Comfort Shaped Suppositories, 16 ct | Bisacodyl 10 mg | 16 | $1.53 | Same | $24.49 | Check price on Amazon |
| Major Bisacodyl 10 mg, 12 ct | Bisacodyl 10 mg | 12 | $0.83 | Per the Drug Facts panel | $9.99 | Check price on Amazon |
| Fleet Glycerin Suppositories, 50 ct | Glycerin 2 g | 50 | $0.09 | 6+; under 6 ask a doctor | $4.29 | Check price on Amazon |
Every Dulcolax suppository listing and the two benchmarks. Strengths are as stated on the listing title or the Drug Facts label. Prices verified via the Amazon Creators API on September 5, 2026. Cost per dose is computed only where the listing states both price and count.
Dulcolax Stimulant Laxative Medicated Suppositories, 4 count
Dulcolax
The reference bisacodyl 10 mg suppository in the box size the occasional-use label calls for.
Our verdict: Four suppositories is the right amount of a stimulant laxative to own. Bisacodyl 10 mg, 15 minutes to 1 hour on the label, individually sealed, from the brand pharmacists mean when they say bisacodyl. At about $1.37 a dose it is the most expensive Dulcolax per unit and still the box to buy, because the label's 1 week line makes a bigger box a question rather than a saving.
Verified: Labeled active: bisacodyl 10 mg per suppository, stimulant laxative, 4 per box. Drug Facts label: relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Live at $5.48 on Amazon, verified via the Creators API on September 5, 2026.
What it is. Dulcolax Stimulant Laxative Medicated Suppositories contain bisacodyl 10 mg per suppository, four to the box, each individually sealed. The Drug Facts label lists relief of occasional constipation and states it generally produces a bowel movement in 15 minutes to 1 hour. Directions: adults and children 12 and over, 1 suppository in a single daily dose; children 6 to under 12, a separate reduced direction printed on the label; under 6, ask a doctor. Bisacodyl is a stimulant laxative: it acts on the bowel wall, which is what makes it the second step after glycerin rather than the first.
What the label says to watch. The bisacodyl label lists abdominal discomfort, faintness and cramps as possible effects, and it carries the standard laxative lines: ask a doctor before use for stomach pain, nausea, vomiting or a sudden change in bowel habits over 2 weeks; stop and ask a doctor for rectal bleeding or no bowel movement after use. The head-to-head with glycerin is in glycerin vs bisacodyl suppositories, the brand matchup is Dulcolax vs Fleet, and the full 10 mg field is in the best bisacodyl suppositories.
Who should buy it
Buy the 4 count if glycerin has not worked for you, a doctor is fine with an occasional stimulant suppository, and you want the reference product in a box that matches the label's occasional-use framing.
What we don't like
It is a stimulant with cramping, discomfort and faintness listed as possible effects, about $1.37 a dose, and the under 6 line is ask a doctor rather than a direction.
- Active ingredient
- Bisacodyl
- Strength
- 10 mg per suppository
- Count
- 4
- Form
- Solid rectal suppository, individually sealed
- Label ages
- 12 and over; 6 to under 12 per label; under 6 ask a doctor
- Cost per dose
- $1.37 ($5.48 divided by 4)
- Packaging
- Boxed, sealed
What we like
- Reference bisacodyl 10 mg from the category brand
- 15 minutes to 1 hour on the label
- Box of 4 fits the occasional-use label
- Individually sealed
Worth noting
- Stimulant; cramps, discomfort and faintness are listed possible effects
- About $1.37 per dose
- Ask a doctor under 6
Dulcolax Stimulant Laxative Medicated Suppositories, 28 count
Dulcolax
The same 10 mg suppository at about 82 cents a dose, for people with a standing reason.
Our verdict: The 28 count is the same suppository at about 82 cents a dose instead of $1.37, and it exists for people whose doctor has set a bowel program or otherwise directed use beyond the label's own 1 week line. For everyone else, 28 stimulant suppositories is a box that will expire before it is used, and the label is telling you why.
Verified: Labeled active: bisacodyl 10 mg per suppository, stimulant laxative, 28 per box per the listing title. Same Drug Facts label as the 4 count. Live at $22.99 on Amazon, verified via the Creators API on September 5, 2026.
Volume, with a caveat. The Dulcolax Medicated Suppositories, 28 count is the same bisacodyl 10 mg under the same Drug Facts label: occasional constipation, 15 minutes to 1 hour, adults and children 12 and over, reduced direction for 6 to under 12, under 6 ask a doctor. At $22.99 (verified via the Amazon Creators API on September 5, 2026) the cost per dose is about 82 cents ($22.99 divided by 28), the lowest of any Dulcolax listing and a hair below Major's generic.
Everything else is identical to the pick, including the listed possible effects and the stop lines: rectal bleeding or no bowel movement after use means stop and ask a doctor. If you are on a bowel program and want the same active in a water-soluble base, our Magic Bullet review covers the alternative.
Who should buy it
Buy the 28 count only if a clinician has directed regular bisacodyl use and you want the lowest cost per dose from the reference brand.
What we don't like
Twenty-eight stimulant suppositories is more than the label's occasional-use framing supports for anyone without a doctor's plan, and most of a box will expire unused in an ordinary household.
- Active ingredient
- Bisacodyl
- Strength
- 10 mg per suppository
- Count
- 28
- Form
- Solid rectal suppository, individually sealed
- Label ages
- 12 and over; 6 to under 12 per label; under 6 ask a doctor
- Cost per dose
- $0.82 ($22.99 divided by 28)
- Packaging
- Boxed, sealed
What we like
- Lowest cost per dose in the Dulcolax line
- Same 10 mg, same label as the 4 count
- Sensible for a clinician-directed program
Worth noting
- Far more than occasional use calls for
- Expiration exposure for an ordinary household
Dulcolax Fast Relief Medicated Laxative Suppositories, 10 mg, 28 count
Dulcolax
A second 28 count listing with the 10 mg strength in the title, about 93 cents a dose.
Our verdict: This is the other 28 count Dulcolax listing, with the 10 mg strength and rectal-use-only line printed in the title. At $25.98 it was about $3 more than the plain 28 count at our check, for the same suppository. Amazon prices move; compare the two before buying and take whichever is lower on the day.
Verified: Labeled active: bisacodyl 10 mg per suppository, stated in the listing title, 28 per box, rectal use only. Same Drug Facts label. Live at $25.98 on Amazon, verified via the Creators API on September 5, 2026.
The same box under a different listing. The Dulcolax Fast Relief Medicated Laxative Suppositories, 28 count listing prints what the plain 28 count does not: bisacodyl 10 mg and rectal use only, right in the title. The product under the label is the same stimulant suppository with the same Drug Facts panel. At $25.98 (verified via the Amazon Creators API on September 5, 2026) the cost per dose is about 93 cents ($25.98 divided by 28).
Same caveat as the plain 28 count: this is a box for a clinician-directed program, not for occasional use, and the label's 1 week line still governs. For which bisacodyl suppository gives the best cost per dose across brands, see the best bisacodyl suppositories.
Who should buy it
Buy this listing instead of the plain 28 count only when it is the cheaper of the two on the day, and only with a clinician's direction for regular use.
What we don't like
About $3 more than the identical plain 28 count at our check, for a title that prints the strength and nothing else.
- Active ingredient
- Bisacodyl
- Strength
- 10 mg per suppository (per listing title)
- Count
- 28
- Form
- Solid rectal suppository, rectal use only
- Label ages
- 12 and over; 6 to under 12 per label; under 6 ask a doctor
- Cost per dose
- $0.93 ($25.98 divided by 28)
- Packaging
- Boxed, sealed
What we like
- Strength printed in the listing title
- Same product as the plain 28 count
Worth noting
- Priced above the identical plain 28 count at our check
- Same occasional-use caveat as any 28 count
Dulcolax Laxative, 10 mg, Comfort Shaped Suppositories, 16 count
Dulcolax
Sixteen suppositories for more than the price of 28, about $1.53 a dose.
Our verdict: The 16 count is the listing to skip on price alone: $24.49 for 16 is about $1.53 a dose, more than the 4 count and nearly double the 28 count. The comfort-shaped units are the same shape the other Dulcolax boxes use. Unless this is the only listing in stock, buy the 4 count or the 28 count instead.
Verified: Labeled active: bisacodyl 10 mg per suppository, stated in the listing title, comfort shaped, 16 per box. Same Drug Facts label. Live at $24.49 on Amazon, verified via the Creators API on September 5, 2026.
The wrong price for the count. Dulcolax Comfort Shaped Suppositories, 16 count print bisacodyl 10 mg in the title and carry the same Drug Facts label as every other Dulcolax suppository. At $24.49 (verified via the Amazon Creators API on September 5, 2026) that is about $1.53 per suppository ($24.49 divided by 16), against 82 cents for the 28 count and $1.37 for the 4 count. A second 16 count listing, Dulcolax Laxative Suppositories, 16 count, was $24.90 at the same check, no better.
Prices move; if either 16 count listing drops below the 28 count, the math changes and it becomes a reasonable middle box. Until then, skip it. The label lines are unchanged: occasional use, 1 week, rectal bleeding or no bowel movement means ask a doctor.
Who should buy it
Buy the 16 count only if it is the sole Dulcolax listing in stock, or if its price has dropped below the 28 count on the day you check.
What we don't like
About $1.53 a dose, more than the 4 count per unit and nearly double the 28 count, for the same suppository.
- Active ingredient
- Bisacodyl
- Strength
- 10 mg per suppository (per listing title)
- Count
- 16
- Form
- Solid rectal suppository, comfort shaped, sealed
- Label ages
- 12 and over; 6 to under 12 per label; under 6 ask a doctor
- Cost per dose
- $1.53 ($24.49 divided by 16)
- Packaging
- Boxed, sealed
What we like
- Strength printed in the listing title
- Same Drug Facts label as the pick
Worth noting
- Costs more than the 28 count for fewer suppositories
- Highest cost per dose in the line
Major Bisacodyl 10 mg Suppositories, 12 count
Major Pharmaceuticals
The pharmacy-generic 10 mg at about 83 cents a dose, 12 comfort-shaped units.
Our verdict: Major is the generic house behind a great deal of hospital and pharmacy stock, and its bisacodyl suppository is the same 10 mg at about 83 cents a dose, a count of 12 that sits between Dulcolax's 4 and 28. For someone who already knows bisacodyl is what their doctor is fine with, this is the value buy against the brand.
Verified: Labeled active: bisacodyl 10 mg per suppository, stimulant laxative, 12 comfort-shaped per the listing title. Labeled for occasional constipation. Live at $9.99 on Amazon, verified via the Creators API on September 5, 2026.
Same strength, no brand premium. Major Bisacodyl 10 mg Suppositories come 12 to the box, comfort-shaped per the listing title, labeled a stimulant laxative for gentle, predictable, fast relief of occasional constipation. At $9.99 (verified via the Amazon Creators API on September 5, 2026) each is about 83 cents ($9.99 divided by 12), effectively tied with Dulcolax's 28 count and far below the 4 count.
Directions and warnings are the bisacodyl set: single daily dose, separate reduced direction for children 6 to under 12, ask a doctor under 6, stop and ask a doctor for rectal bleeding or no bowel movement after use, not more than 1 week without a doctor. The generic field, including Paddock and NeilMed, is ranked in the best bisacodyl suppositories.
Who should buy it
Buy Major instead of Dulcolax if you already know bisacodyl is right for you, a doctor is fine with it, and you want the standard 10 mg at the lowest sensible cost per dose.
What we don't like
A generic box with no consumer-brand support, and 12 stimulant suppositories is still more than a genuinely occasional user will use before the expiry.
- Active ingredient
- Bisacodyl
- Strength
- 10 mg per suppository
- Count
- 12
- Form
- Solid rectal suppository, comfort-shaped
- Label ages
- Per the Drug Facts panel (bisacodyl standard: 12 and over; 6 to under 12 per label; under 6 ask a doctor)
- Cost per dose
- $0.83 ($9.99 divided by 12)
- Packaging
- Boxed
What we like
- Standard 10 mg at about 83 cents a dose
- Middle count of 12
- Generic house that supplies pharmacies
Worth noting
- No consumer brand behind the box
- Still occasional use only
Fleet Glycerin Suppositories, 50 count
Fleet
The glycerin suppository the label logic says to try before any stimulant, about 9 cents a dose.
Our verdict: Fleet is not a Dulcolax competitor so much as the step before it. Glycerin draws water into the bowel rather than stimulating it, its label carries the same 15 minutes to 1 hour with none of the stimulant's listed effects, and it costs about 9 cents a dose. If you have not tried glycerin, the label logic says start here.
Verified: Labeled active: glycerin 2 g per adult suppository, 50 per jar. Drug Facts label: relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Live at $4.29 on Amazon, verified via the Creators API on September 5, 2026.
The first step. Fleet Glycerin Suppositories, 50 count are glycerin 2 g, hyperosmotic, labeled for occasional constipation with a bowel movement generally in 15 minutes to 1 hour. Directions: adults and children 6 and over, 1 suppository once daily; under 6, ask a doctor. At $4.29 (verified via the Amazon Creators API on September 5, 2026) for 50, that is about 9 cents a dose ($4.29 divided by 50).
The full write-up is our Fleet Glycerin Suppositories review, and the direct matchup is Dulcolax vs Fleet suppositories.
Who should buy it
Buy Fleet before Dulcolax if you have not tried a glycerin suppository, or if a doctor has told you to avoid stimulant laxatives.
What we don't like
Loose in a jar rather than sealed, softens in heat, and no direction for children under 6.
- Active ingredient
- Glycerin
- Strength
- 2 g per suppository
- Count
- 50
- Form
- Solid rectal suppository, jar
- Label ages
- 6 and over; under 6 ask a doctor
- Cost per dose
- $0.09 ($4.29 divided by 50)
- Packaging
- Jar, not individually wrapped
What we like
- Not a stimulant; none of bisacodyl's listed effects
- Same 15 minutes to 1 hour on the label
- About 9 cents a dose
Worth noting
- Loose in a jar, softens in heat
- No direction under 6
What you'll need
The six things that go in the same cart as a suppository: the pharmacy-standard glycerin, a daily stool softener, an enema for the nights nothing else works, witch hazel wipes, sitz salts, and a barrier ointment. Prices are approximate at time of writing.
More picks worth comparing
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Quick shop: every pick
Skip the scroll: the whole lineup, with a live price check on each.
- Dulcolax Stimulant Laxative Medicated Suppositories, 4 countBest OverallDulcolax · $5.48Check price on Amazon
- Dulcolax Stimulant Laxative Medicated Suppositories, 28 countBest Per-Dose PriceDulcolax · $22.99Check price on Amazon
- Dulcolax Fast Relief Medicated Laxative Suppositories, 10 mg, 28 countBest Alternate 28 Count ListingDulcolax · $25.98Check price on Amazon
- Dulcolax Laxative, 10 mg, Comfort Shaped Suppositories, 16 countThe One to SkipDulcolax · $24.49Check price on Amazon
- Major Bisacodyl 10 mg Suppositories, 12 countBenchmark: The GenericMajor Pharmaceuticals · $9.99Check price on Amazon
- Fleet Glycerin Suppositories, 50 countBenchmark: The Non-StimulantFleet · $4.29Check price on Amazon
How we chose
This review is built on the Drug Facts panel and the live listing. For every Dulcolax suppository SKU on Amazon we recorded the active and strength (bisacodyl 10 mg, stated on the label and on several of the titles), the count, the packaging, the label's age bands, and the price on September 5, 2026 via the Creators API. Cost per dose is shown with the division wherever the title gives a count. Owner reports were weighed for consistency on the things a label cannot tell you: whether the sealed units arrive intact, whether the comfort-shaped units are easier to use, and how consistently the label's window holds in practice.
Compliance for a stimulant laxative: we quote the label's Uses and Directions and nothing beyond them. Bisacodyl suppositories are for occasional constipation, not routine use; the label says not more than 1 week without a doctor, and it lists abdominal discomfort, faintness and cramps as possible effects, which we repeat rather than soften. We carry every age band, and the stop lines every laxative shares: rectal bleeding or no bowel movement after use means stop and ask a doctor. For any child, the pediatrician decides. We are a research and verification desk, not a pharmacy or a clinic, and nothing on this page is medical advice. No brand paid for a placement and none saw this review before publication.
Questions, answered
How long does a Dulcolax suppository take to work?
The Drug Facts label states that it generally produces a bowel movement in 15 minutes to 1 hour. That is the same window printed on glycerin suppository labels; the difference is mechanism, not speed. If you have no bowel movement after use, the label says stop and ask a doctor.
How much bisacodyl is in a Dulcolax suppository?
10 mg per suppository, stated on the Drug Facts label and printed in several of the Amazon listing titles. That is the standard strength across the bisacodyl suppository category, including Major's generic and NeilMed's.
Can I use Dulcolax suppositories every day?
Not without a doctor. The label lists occasional constipation as the use and says not to use for more than 1 week unless directed by a doctor. Bisacodyl is a stimulant laxative, and the label's own framing is occasional. If you need one regularly, that is a conversation with a clinician, and the 28 count exists for people who have had it.
Which Dulcolax suppository box should I buy?
The 4 count at $5.48 at our September 5, 2026 check, about $1.37 a dose, for occasional use. The 28 count at $22.99 is about 82 cents a dose and makes sense only with a clinician's direction for regular use. Skip the 16 count, which at $24.49 costs more than the 28 count for fewer suppositories.
Is Dulcolax or Fleet better?
They are different laxatives. Fleet is glycerin, hyperosmotic, not a stimulant, about 9 cents a dose, and the product to try first. Dulcolax is bisacodyl 10 mg, a stimulant with cramps and discomfort listed as possible effects, about $1.37 a dose in the 4 count, and the product to move to if glycerin has not worked and a doctor is fine with a stimulant. Both labels state 15 minutes to 1 hour.
Can a child use a Dulcolax suppository?
The label covers adults and children 12 and over at 1 suppository daily, prints a separate reduced direction for children 6 to under 12, and says ask a doctor under 6. The pediatrician decides for any child, and for young children the pediatric glycerin products have labels that cover their ages.
What are the side effects listed on the Dulcolax suppository label?
The label lists abdominal discomfort, faintness and cramps as possible effects, and carries the standard laxative lines: ask a doctor before use for stomach pain, nausea, vomiting or a sudden change in bowel habits over 2 weeks; stop and ask a doctor for rectal bleeding or no bowel movement after use. Read the box you buy; the panel is the authority.
Is Major bisacodyl the same as Dulcolax?
Same active and strength, bisacodyl 10 mg, in a comfort-shaped suppository from a pharmacy-generic house. Major's 12 count at $9.99 at our check is about 83 cents a dose, close to Dulcolax's 28 count and far below its 4 count. What you give up is the consumer brand.
Filed under Review
Keep reading
Best Bisacodyl Suppositories (2026)
Dulcolax, Major, Paddock and NeilMed at 10 mg, ranked on cost per dose and the occasional-use label.
Dulcolax Suppository vs Tablets
Rectal 10 mg in under an hour or oral overnight: the two labels side by side.
Dulcolax vs Fleet Suppositories
Stimulant against hyperosmotic, the same table on both sides, and which to try first.
Glycerin vs Bisacodyl Suppositories
The mechanism difference the label draws, and why glycerin comes first.