Dulcolax vs Fleet Suppositories: The Two Brand Lines, Box by Box

Fleet for the first try, Dulcolax for the stimulant step, and the boxes each brand sells decide the rest. Fleet Glycerin Suppositories, 50 count, at $4.29 is about 9 cents a dose and non-stimulant. Dulcolax Medicated Suppositories, 4 count, at $5.48 is bisacodyl 10 mg at about $1.37 a dose with cramping on the label. Fleet also sells the liquid glycerin applicator for anyone who will not use a solid. Prices verified via the Amazon Creators API on September 5, 2026.

By The Pharmacy Desk2026-09-05~10 min read Ranked on verified label facts, never box claimsHow we research

Fleet Glycerin Suppositories, 50 countBest Overall

Fleet Glycerin Suppositories, 50 count

Fleet · 4.8

$4.29

Dulcolax Stimulant Laxative Medicated Suppositories, 4 countBest Value

Dulcolax Stimulant Laxative Medicated Suppositories, 4 count

Dulcolax · 4.6

$5.48

Fleet Liquid Glycerin Suppositories, 4 applicatorsUpgrade Pick

Fleet Liquid Glycerin Suppositories, 4 applicators

Fleet · 4.6

$5.58

Buy Fleet Glycerin Suppositories, 50 count, at $4.29 (verified via the Amazon Creators API on September 5, 2026) unless a doctor has told you a stimulant is fine. Fleet's suppository is glycerin 2 g, hyperosmotic, labeled for 15 minutes to 1 hour, and about 9 cents a dose. Dulcolax Stimulant Laxative Medicated Suppositories, 4 count, at $5.48 is bisacodyl 10 mg, a stimulant with the same window on its label and about $1.37 a dose. The brands are not competing for the same moment: Fleet is the first try, Dulcolax is the next step.

What this page adds to the ingredient comparison in glycerin vs bisacodyl is the box-level view. Each brand sells a ladder of sizes and formats, and the ladder matters: Fleet's 100 count jar is cheaper per dose than its 50, Fleet's liquid glycerin applicator is the same active for people who will not handle a solid, Dulcolax's 4 count matches its occasional-use label better than its 28 count does, and both brands sell things that are not suppositories at all (Fleet enemas, Dulcolax tablets and stool softeners). We sort all of it below.

Both are over-the-counter drugs with Drug Facts panels, and we quote them rather than improvise. Both labels say occasional constipation, both say not to use for more than 1 week unless a doctor directs, and both say stop and ask a doctor for rectal bleeding or no bowel movement after use. We are a research and verification desk, not clinicians; nothing here is medical advice, no brand has paid for a placement, and if you buy through a link we may earn an Amazon commission at no cost to you.

The short version

  • Fleet Glycerin 50 count ($4.29, about 9 cents a dose) is the first try: hyperosmotic, non-stimulant, 15 minutes to 1 hour, ages 6 and over on the label.
  • Dulcolax Medicated Suppositories 4 count ($5.48, about $1.37 a dose) is the stimulant step: bisacodyl 10 mg, same window, cramping and faintness listed as possible effects, main direction 12 and over.
  • Within Fleet: the 100 count jar at $7.23 is about 7 cents a dose; the 50 count 3-pack at $13.07 saves nothing per dose; Fleet Liquid Glycerin at $5.58 for 4 is the same active in a pre-filled applicator.
  • Within Dulcolax: the 4 count matches the occasional-use label; the 28 count boxes at $22.99 and $25.98 bring the per-dose price to 82 to 93 cents but are a lot of stimulant to own.
  • Neither brand's suppository label covers children under 6 with anything but ask a doctor; Fleet's Pedia-Lax line is the pediatric shelf.

At a glance

ProductActiveTypeLabel timeWrapped?Cost per dosePrice (9/5/26)Check price
Fleet Glycerin Suppositories, 50 ctGlycerin 2 gHyperosmotic15 min to 1 hrNo, jar$0.09$4.29Check price on Amazon
Dulcolax Medicated Suppositories, 4 ctBisacodyl 10 mgStimulant15 min to 1 hrYes, sealed$1.37$5.48Check price on Amazon
Fleet Liquid Glycerin, 4 applicatorsGlycerin (liquid)Hyperosmotic15 min to 1 hrSealed applicators$1.40$5.58Check price on Amazon

The two subject boxes and the Fleet liquid applicator. Active and strength come from the Drug Facts panel; counts from the listing title. Cost per dose is computed only where the title states the count. Prices verified via the Amazon Creators API on September 5, 2026.

Our PickThe First Try
Fleet Glycerin Suppositories, 50 count

Fleet Glycerin Suppositories, 50 count

Fleet

Glycerin 2 g, non-stimulant, 15 minutes to 1 hour, about 9 cents a dose from the reference brand.

4.8

Our verdict: Fleet's jar is where this shelf starts. Glycerin draws water into the lower bowel and softens stool; the label carries no cramping or faintness line, covers adults and children 6 and over, and prints the same 15 minutes to 1 hour as Dulcolax. At about 9 cents a dose it is the cheapest suppository either brand sells.

Verified: Labeled active: glycerin 2 g per adult suppository (Drug Facts panel), 50 per jar. Uses: relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Live at $4.29 on Amazon, verified via the Creators API on September 5, 2026.

The Fleet suppository. Fleet Glycerin Suppositories, 50 count are solid adult glycerin suppositories, 2 g each per the Drug Facts panel, loose in a jar. Uses: relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Directions: adults and children 6 years and over, 1 suppository once daily or as directed by a doctor; children under 6, ask a doctor.

The Fleet ladder: the 100 count jar at $7.23 is about 7 cents a dose ($7.23 divided by 100), the best per-dose price either brand sells. The 50 count 3-pack at $13.07 is about 9 cents, no cheaper than one jar; buy it for three sealed jars, not for savings. Prices verified via the Amazon Creators API on September 5, 2026.

Where Fleet's jar loses to Dulcolax's box: packaging. Fleet's suppositories are not wrapped and soften in a warm bathroom or summer shipping; Dulcolax's are sealed. If that is the decider, the wrapped glycerin alternative is NeilMed rather than switching actives. The shared stop lines apply: rectal bleeding or no bowel movement after use means stop and ask a doctor, and no laxative beyond 1 week without one. The full brand write-up is the Fleet Glycerin Suppositories review.

Who should buy it

Buy Fleet glycerin if you want the non-stimulant first try at the lowest cost per dose, and a jar in the cabinet suits you better than a small sealed box.

What we don't like

Not wrapped, softens in heat, and the 2 g strength is on the panel rather than the listing title.

Active ingredient
Glycerin
Strength
2 g per suppository (per the Drug Facts panel)
Count
50
Form
Solid rectal suppository, jar
Label ages
6 years and over; under 6 ask a doctor
Cost per dose
$0.09 ($4.29 divided by 50)
Packaging
Jar, not individually wrapped

What we like

  • Non-stimulant; no cramping line on the label
  • About 9 cents a dose; 7 cents in the 100 count
  • Label covers children 6 and over

Worth noting

  • Not individually wrapped
  • Softens in heat
Best ValueThe Stimulant Step
Dulcolax Stimulant Laxative Medicated Suppositories, 4 count

Dulcolax Stimulant Laxative Medicated Suppositories, 4 count

Dulcolax

Bisacodyl 10 mg, sealed, 15 minutes to 1 hour, a box sized for the occasional-use label.

4.6

Our verdict: Dulcolax is the reference bisacodyl suppository and the 4 count is the box that matches its label: occasional use, 1 week maximum without a doctor. It is sealed, it prints 10 mg, and it carries the stimulant's possible effects (abdominal discomfort, faintness, rectal burning, mild cramps). At about $1.37 a dose it is fifteen times Fleet glycerin, which is the price of a different active, not a better one.

Verified: Labeled active: bisacodyl 10 mg per suppository, stimulant laxative, 4 per box. Uses: relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Live at $5.48 on Amazon, verified via the Creators API on September 5, 2026.

The Dulcolax suppository. Dulcolax Medicated Suppositories, 4 count are bisacodyl 10 mg, individually sealed. The Drug Facts panel reads relief of occasional constipation, 15 minutes to 1 hour, rectal use only. Directions: adults and children 12 years and over, 1 suppository in a single daily dose; children 6 to under 12, a reduced direction printed on the box; under 6, ask a doctor. Possible effects listed: abdominal discomfort, faintness, rectal burning, mild cramps.

The Dulcolax ladder: the 28 count at $22.99 is about 82 cents a dose ($22.99 divided by 28); the Fast Relief 28 count, whose title prints bisacodyl 10 mg, is $25.98, about 93 cents; the Comfort Shaped 16 count at $24.49 is about $1.53, more per dose than the 4 count. Prices verified September 5, 2026. For a product labeled occasional use and 1 week, the 4 count is the sensible box; the 28 counts are for a household where a doctor has directed regular use.

Not suppositories, but on the same listing page: Dulcolax also sells stimulant laxative tablets (bisacodyl by mouth, labeled for 6 to 12 hours) and a docusate stool softener. The suppository-versus-tablet call is Dulcolax suppository vs tablets; the line write-up is the Dulcolax suppositories review. The wrapped bisacodyl alternative is NeilMed Bisacodyl Suppositories at $8.28 (count not in the title).

Who should buy it

Buy Dulcolax if glycerin has not produced a bowel movement, a doctor is fine with an occasional stimulant, and you want a sealed box sized for occasional use.

What we don't like

A stimulant with cramping and faintness on the label, about $1.37 a dose in the box that fits the label, and a main direction that starts at 12.

Active ingredient
Bisacodyl
Strength
10 mg per suppository
Count
4
Form
Solid rectal suppository, individually sealed
Label ages
12 and over; 6 to under 12 per label; under 6 ask a doctor
Cost per dose
$1.37 ($5.48 divided by 4)
Packaging
Boxed, sealed

What we like

  • Reference bisacodyl 10 mg, printed strength
  • Sealed units travel and store well
  • Box size matches the occasional-use label

Worth noting

  • Stimulant; cramps and faintness on the label
  • About $1.37 a dose
Upgrade PickIf Neither: No Solid to Handle
Fleet Liquid Glycerin Suppositories, 4 applicators

Fleet Liquid Glycerin Suppositories, 4 applicators

Fleet

Fleet's glycerin in a pre-filled applicator: same label window, sealed, nothing to unwrap or warm.

4.6

Our verdict: If the objection to both boxes is the solid suppository, Fleet's liquid applicator answers it without switching to a stimulant. The Drug Facts label carries the same 15 minutes to 1 hour and the same 6 and over direction. At about $1.40 per use it costs what Dulcolax costs, for a non-stimulant. Dulcolax has no equivalent format.

Verified: Labeled active: glycerin, liquid, single-use pre-filled applicator, 4 per box. Uses: relief of occasional constipation; generally produces a bowel movement in 15 minutes to 1 hour. Live at $5.58 on Amazon, verified via the Creators API on September 5, 2026.

The format Dulcolax does not sell. Fleet Liquid Glycerin Suppositories put glycerin in a small pre-filled applicator with an insertion tip. The label reads relief of occasional constipation, 15 minutes to 1 hour, adults and children 6 years and over, under 6 ask a doctor. The listing title does not state the glycerin amount per applicator; the Drug Facts panel does.

The math: $5.58 divided by 4 is about $1.40 per use (verified September 5, 2026), the same money as a Dulcolax suppository, for a hyperosmotic rather than a stimulant. The 3-pack at $17.37 for 12 is about $1.45, no cheaper. Buy the liquid for the format, not the price.

Fleet's other non-suppository answer is the Fleet Saline Enema at $2.84 for 2, labeled for 1 to 5 minutes and, like every enema, for occasional use only; that comparison is suppository vs enema. The liquid glycerin field is ranked in the best liquid glycerin suppositories.

Who should buy it

Buy the liquid applicator if a solid suppository is the reason you are hesitating over either brand, and a non-stimulant is still the goal.

What we don't like

About fifteen times the jar's cost per dose, only 4 per box, and the amount per applicator is not on the listing title.

Active ingredient
Glycerin (liquid)
Strength
Not stated on the listing title; on the Drug Facts panel
Count
4 single-use applicators
Form
Pre-filled rectal applicator
Label ages
6 years and over; under 6 ask a doctor
Cost per dose
$1.40 ($5.58 divided by 4)
Packaging
Boxed, each applicator sealed

What we like

  • No solid to handle; sealed applicators
  • Non-stimulant with the same label window
  • A format Dulcolax does not offer

Worth noting

  • About $1.40 per use
  • Amount per applicator not on the title

What you'll need

The six things that go in the same cart as a suppository: the pharmacy-standard glycerin, a daily stool softener, an enema for the nights nothing else works, witch hazel wipes, sitz salts, and a barrier ointment. Prices are approximate at time of writing.

What each brand actually sells as a suppository

Fleet sells one rectal suppository active, glycerin, in two formats: the solid jar (50 count, 100 count, and multi-packs of each) and the liquid pre-filled applicator (4 count and a 3-pack). Everything else under the Fleet name on this shelf is an enema (saline, mineral oil, children's) or the Pedia-Lax pediatric line. Dulcolax sells one rectal suppository active, bisacodyl 10 mg, in four boxes (4, 16, 28 and 28 Fast Relief), and then a shelf of oral products: bisacodyl tablets, liquid gels, a docusate stool softener, saline liquid and chews, and gummies.

So the brand comparison is really a glycerin-versus-bisacodyl comparison with a packaging story on top. The mechanism half is covered in full at glycerin vs bisacodyl suppositories; the short version is that glycerin draws water in and bisacodyl stimulates the bowel wall, both labels print 15 minutes to 1 hour, and only the bisacodyl label lists cramping and faintness.

Packaging: jar versus sealed box

This is the axis where Dulcolax wins cleanly. Every Dulcolax suppository is individually sealed; every Fleet solid suppository is loose in a jar. Owners of the Fleet jar consistently report softened suppositories after summer shipping or a warm bathroom, and the fix (chill the sealed jar briefly, do not use one that has lost its shape) is covered in what to do when a suppository melts. Dulcolax owners rarely report the problem.

But packaging is not a reason to change actives. If a wrapped unit is what you need and glycerin is what you should be using, the answer is NeilMed Glycerin Suppositories, wrapped, 30 for $9.19 (about 31 cents each), or the sealed Fleet liquid applicator. Moving to a stimulant because the box is nicer is the wrong reason.

Label ages: who each box is directed for

Fleet's adult glycerin label directs use for adults and children 6 years and over, with under 6 sent to a doctor. Dulcolax's label directs adults and children 12 years and over, prints a reduced direction for children 6 to under 12, and sends under 6 to a doctor. For a household with school-age children, Fleet's label covers more of them in its main direction.

Under 6 is a separate conversation and a separate shelf. Fleet's pediatric line, Pedia-Lax, includes a liquid glycerin applicator labeled for ages 2 to 5 and a children's saline enema; the pediatrician decides whether any laxative is appropriate. See Fleet vs Pedia-Lax and the Pedia-Lax review. Dulcolax has no pediatric suppository in the catalog.

Cost per dose across both ladders

All prices verified via the Amazon Creators API on September 5, 2026; cost per dose computed only where the listing title states the count.

BoxActiveCountCost per dosePrice (9/5/26)
Fleet Glycerin, 100 ct jarGlycerin 2 g100$0.07$7.23
Fleet Glycerin, 50 ct jarGlycerin 2 g50$0.09$4.29
Fleet Glycerin, 50 ct x 3Glycerin 2 g150$0.09$13.07
Dulcolax Medicated, 28 ctBisacodyl 10 mg28$0.82$22.99
Dulcolax Fast Relief, 28 ctBisacodyl 10 mg28$0.93$25.98
Dulcolax Medicated, 4 ctBisacodyl 10 mg4$1.37$5.48
Fleet Liquid Glycerin, 4Glycerin (liquid)4$1.40$5.58
Dulcolax Comfort Shaped, 16 ctBisacodyl 10 mg16$1.53$24.49

The Fleet jar is in a different price class from anything Dulcolax sells. Within Dulcolax, note that the 16 count is the worst per dose in the line, worse than the 4 count; if you are buying Dulcolax in volume on a doctor's direction, the plain 28 count is the box.

Warnings both labels share, and the ones only Dulcolax carries

Shared: ask a doctor before use if you have stomach pain, nausea or vomiting, or a sudden change in bowel habits lasting over 2 weeks; stop use and ask a doctor if you have rectal bleeding or no bowel movement after use; do not use a laxative for more than 1 week unless directed by a doctor. Dulcolax only: may cause abdominal discomfort, faintness, rectal burning and mild cramps; rectal use only. Fleet's glycerin label carries no such block, which is the whole reason it is the first try.

The line to take seriously on both: if the suppository did not produce a bowel movement, the label says ask a doctor. Owners sometimes read that as permission to try the other brand. It is not. It is the label's way of saying the cause may not be what a laxative can fix.

The verdict, by buyer

  • Occasional constipation, first purchase: Fleet Glycerin, 50 count.
  • More than one adult in the house, or doctor-directed regular use: Fleet Glycerin, 100 count, about 7 cents a dose.
  • Glycerin did not work and a doctor is fine with a stimulant: Dulcolax 4 count.
  • Need a sealed unit for travel or a hot bathroom, still want glycerin: NeilMed Glycerin or the Fleet liquid applicator.
  • Will not use a solid suppository: the Fleet liquid applicator; Dulcolax has no equivalent.
  • Child under 6: neither adult box. Fleet's Pedia-Lax line and the pediatrician.

More picks worth comparing

Beyond this guide, the highest-rated picks across every category and budget, with a live price check on each.

Fleet Glycerin, Adult 50 ct

Best Overall

Fleet Glycerin, Adult 50 ct

glycerin · 50 ct · ~$4

Check Price
Dulcolax Bisacodyl 10 mg

Best Fast-Acting

Dulcolax Bisacodyl 10 mg

bisacodyl · 4 ct · ~$5

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Preparation H Suppositories

Best for Hemorrhoids

Preparation H Suppositories

12 ct x 2 · ~$18

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pH-D Boric Acid 600 mg

Best Boric Acid

pH-D Boric Acid 600 mg

600 mg · 24 ct · ~$27

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Pedia-Lax Liquid Glycerin, Kids

Best for Kids

Pedia-Lax Liquid Glycerin, Kids

ages 2 to 5 · 6 ct x 3 · ~$21

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FeverAll Infant 80 mg

Best Fever

FeverAll Infant 80 mg

acetaminophen · 6 ct · ~$13

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Quick shop: every pick

Skip the scroll: the whole lineup, with a live price check on each.

  1. Fleet Glycerin Suppositories, 50 countThe First TryFleet · $4.29Check price on Amazon
  2. Dulcolax Stimulant Laxative Medicated Suppositories, 4 countThe Stimulant StepDulcolax · $5.48Check price on Amazon
  3. Fleet Liquid Glycerin Suppositories, 4 applicatorsIf Neither: No Solid to HandleFleet · $5.58Check price on Amazon

How we chose

We compared the two brand lines on the Drug Facts panel first (active, strength, Uses, Directions and age lines, warnings and stop lines) and then on the boxes each brand sells: count, packaging, whether units are wrapped, and cost per dose computed only where the listing title states the count. Every price was verified via the Amazon Creators API on September 5, 2026. Owner reports were weighed for the practical differences a label cannot tell you: how the jar and the sealed box travel, whether the liquid applicator tip is comfortable, and how owners describe the feel of a stimulant against a hyperosmotic.

Compliance for this shelf: we quote the label's Uses and Directions and nothing beyond them. We never suggest a dose the label does not print, we carry every age cut-off, and we repeat the stop lines every laxative label shares: rectal bleeding, no bowel movement after use, or use beyond 1 week mean stop and ask a doctor. Stimulant laxatives are for occasional use. For any child, the pediatrician decides. Nothing on this page is medical advice.

Questions, answered

Is Dulcolax or Fleet better for constipation?

They are different actives for different moments. Fleet's suppository is glycerin 2 g, a non-stimulant hyperosmotic labeled for 15 minutes to 1 hour, about 9 cents a dose in the 50 count jar; try it first. Dulcolax's suppository is bisacodyl 10 mg, a stimulant with the same window on the label and cramping listed as a possible effect, about $1.37 a dose in the 4 count; it is the step after glycerin, with a doctor's nod.

Do Dulcolax and Fleet suppositories work in the same amount of time?

Per the labels, yes: both Drug Facts panels state generally produces a bowel movement in 15 minutes to 1 hour. The difference is mechanism and warnings, not speed.

Which Fleet box is the best value?

The 100 count jar at $7.23 (about 7 cents a dose at our September 5, 2026 check). The 50 count at $4.29 is about 9 cents; the 50 count 3-pack at $13.07 is also about 9 cents, so it saves nothing per dose over a single jar.

Which Dulcolax box is the best value?

Per dose, the plain 28 count at $22.99 (about 82 cents). The Fast Relief 28 count at $25.98 is about 93 cents, the 4 count at $5.48 is about $1.37, and the 16 count at $24.49 is about $1.53, the worst in the line. Given the label's occasional-use and 1 week lines, the 4 count is the sensible box for most buyers.

Are Dulcolax suppositories individually wrapped? Are Fleet's?

Dulcolax suppositories are individually sealed. Fleet's solid glycerin suppositories are loose in a jar, which is why owners report softening in heat. Fleet's liquid glycerin applicators are sealed. For wrapped glycerin, NeilMed sells them at about 31 cents each.

Can children use Dulcolax or Fleet suppositories?

Fleet adult glycerin: 6 years and over, under 6 ask a doctor. Dulcolax: 12 and over as the main direction, a reduced direction on the box for 6 to under 12, under 6 ask a doctor. Under 6 is a pediatric shelf (Fleet's Pedia-Lax liquid glycerin is labeled for ages 2 to 5) and the pediatrician decides.

Does Fleet make a bisacodyl suppository, or Dulcolax a glycerin one?

Not in the catalog. Fleet's rectal suppository is glycerin (solid and liquid); Dulcolax's is bisacodyl 10 mg. Dulcolax's other products are oral: tablets, liquid gels, a docusate stool softener, saline liquid and chews.