How to Use a Rectal Suppository: Laxative, Hemorrhoidal and Fever Types

A rectal suppository is inserted pointed end first about an inch past the muscle at the opening, with you lying on your side, and you stay down for about 15 minutes. What happens after that depends on the product: a glycerin or bisacodyl laxative is labeled for a bowel movement in 15 minutes to 1 hour, a hemorrhoidal suppository simply coats the tissue, and an acetaminophen suppository is absorbed for fever. This guide covers each type, plus the pre-filled liquid glycerin applicator, exactly as the labels direct.

By The Best Suppositories Desk2026-09-05~9 min read Ranked on verified label facts, never box claimsHow we research

Use a rectal suppository the same way regardless of what is in it: wash your hands, chill the suppository if it is soft, unwrap it, moisten the pointed end with water, lie on your left side with the upper knee bent, push it in pointed end first until it passes the muscle (about 1 inch for an adult), squeeze your buttocks together for a few seconds, and stay lying down for about 15 minutes. For a laxative such as the Fleet Glycerin Suppository at $4.29 for 50 (verified via the Amazon Creators API on September 5, 2026), the Drug Facts label states a bowel movement generally follows in 15 minutes to 1 hour, so plan around a bathroom.

The four rectal types on the OTC shelf differ in what the label directs after insertion, not in how they go in. Glycerin (Fleet, NeilMed) is hyperosmotic and draws water into the bowel. Bisacodyl 10 mg (Dulcolax) is a stimulant laxative for occasional use. Hemorrhoidal suppositories (Preparation H) coat and constrict internal tissue up to 4 times daily. Acetaminophen (FeverAll) is absorbed into the bloodstream to reduce a child's fever, dosed by age on the box. And Fleet Liquid Glycerin is glycerin in a pre-filled applicator with a different insertion routine, covered below.

This page explains technique and quotes labels. It is not medical advice; a doctor or pharmacist decides which product, if any, is right for you, and for a child the pediatrician decides. Every laxative label says to stop and ask a doctor for rectal bleeding or no bowel movement after use, and not to use laxatives for more than 1 week. If you buy through a link we may earn an Amazon commission at no cost to you.

The short version

  • Same insertion for every rectal type: side-lying, pointed end first, about 1 inch in for an adult, then 15 minutes lying down.
  • Glycerin and bisacodyl labels both state 15 minutes to 1 hour to a bowel movement; one suppository daily is the direction, occasional use only.
  • Liquid glycerin comes in a pre-filled applicator: insert the tip, squeeze, remove; same 15 minutes to 1 hour on the label.
  • Hemorrhoidal suppositories: up to 4 times daily per the Preparation H label, stop and ask a doctor after 7 days or if bleeding occurs.
  • Acetaminophen suppositories are dosed by age on the FeverAll box; under 6 months ask a doctor, and the AAP says any fever under 3 months is a call to the doctor.

Our top-rated suppositories

Whatever you decide, these are the picks we recommend across every shelf, ranked on verified label facts and cost per dose. Live price check on each.

Fleet Glycerin, Adult 50 ct

Best Overall

Fleet Glycerin, Adult 50 ct

glycerin · 50 ct · ~$4

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Dulcolax Bisacodyl 10 mg

Best Fast-Acting

Dulcolax Bisacodyl 10 mg

bisacodyl · 4 ct · ~$5

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Preparation H Suppositories

Best for Hemorrhoids

Preparation H Suppositories

12 ct x 2 · ~$18

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pH-D Boric Acid 600 mg

Best Boric Acid

pH-D Boric Acid 600 mg

600 mg · 24 ct · ~$27

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Pedia-Lax Liquid Glycerin, Kids

Best for Kids

Pedia-Lax Liquid Glycerin, Kids

ages 2 to 5 · 6 ct x 3 · ~$21

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FeverAll Infant 80 mg

Best Fever

FeverAll Infant 80 mg

acetaminophen · 6 ct · ~$13

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What you'll need

The six things that go in the same cart as a suppository: the pharmacy-standard glycerin, a daily stool softener, an enema for the nights nothing else works, witch hazel wipes, sitz salts, and a barrier ointment. Prices are approximate at time of writing.

The insertion routine every rectal suppository shares

Prepare: wash your hands, and if the suppository feels soft in its wrapper, chill it in the refrigerator for 15 to 30 minutes or under cold running water; a firm suppository inserts cleanly and a soft one smears. Unwrap it and moisten the pointed end with a little water. Position: lie on your left side, lower leg straight, upper knee bent toward your chest. Insert: lift the upper buttock, breathe out, and push the suppository in pointed end first with your index finger until it passes the muscle at the opening and you feel it move freely, about 1 inch for an adult. Hold: withdraw your finger, squeeze your buttocks together for a few seconds, and stay lying down for about 15 minutes.

That routine is identical for glycerin, bisacodyl, hemorrhoidal and acetaminophen suppositories. Where they differ is what the label directs next, and that is the rest of this page. If you want the full flagship walkthrough with the vaginal route and child technique, it is in how to insert a suppository.

Two rules that prevent most problems: water, not petroleum jelly, on the tip; and about 1 inch of depth so the suppository is past the muscle and stays in.

Glycerin suppositories: what the Fleet label directs

The Fleet Glycerin Suppositories Drug Facts label states glycerin 2 g per adult suppository, lists the use as relief of occasional constipation, and states that it generally produces a bowel movement in 15 minutes to 1 hour. Directions: adults and children 6 years and over, 1 suppository once daily or as directed by a doctor; children under 6, ask a doctor. The jar works out to about 9 cents a suppository ($4.29 divided by 50 at our September 5, 2026 check), which is why it is the reference product on the shelf. The individually wrapped alternative is NeilMed Glycerin Suppositories at $9.19, which owners prefer for travel and warm bathrooms.

After insertion, hold it as long as the urge allows within the first 15 minutes; glycerin works by drawing water into the lower bowel and softening what is there, and owners consistently report a more complete result when the suppository has had time to dissolve. What the label says to watch: ask a doctor before use if you have stomach pain, nausea or vomiting, or a sudden change in bowel habits lasting over 2 weeks; stop use and ask a doctor if you have rectal bleeding or fail to have a bowel movement after use; do not use laxative products for more than 1 week unless directed by a doctor. Timing in more detail is in how long a glycerin suppository takes to work.

Bisacodyl suppositories: the Dulcolax label and the stimulant caveat

Dulcolax Medicated Suppositories contain bisacodyl 10 mg, a stimulant laxative. The label states it generally produces a bowel movement in 15 minutes to 1 hour, the same window as glycerin, but the mechanism is different: bisacodyl acts on the bowel wall rather than drawing in water, and the label lists abdominal discomfort, faintness, rectal burning and mild cramps as possible effects. Directions: adults and children 12 years and over, 1 suppository in a single daily dose; children 6 to under 12 years, one half suppository in a single daily dose; children under 6, ask a doctor. It is one of the few labels on this shelf that directs cutting a suppository.

Insertion is the standard routine, and the label's own note is that the suppository should be inserted well into the rectum. The stimulant caveat matters: every stimulant laxative label says occasional use, and the 1-week line applies. Most pharmacists and the labels themselves put glycerin first and bisacodyl second, for when glycerin has not worked and a doctor is fine with a stimulant. The comparison is in glycerin vs bisacodyl suppositories, and the bisacodyl field is ranked in the best bisacodyl suppositories.

Liquid glycerin: how the pre-filled applicator works

Fleet Liquid Glycerin Suppositories put the same glycerin into a small squeeze bottle with a soft, pre-lubricated tip, 4 to a box at $5.58 (verified via the Amazon Creators API on September 5, 2026), about $1.40 each. The routine changes because there is no solid to handle: remove the protective cap, lie on your side with the upper knee bent, gently insert the tip into the rectum with the bottle pointed slightly toward your back, squeeze until the bottle is nearly empty, and withdraw it while still squeezing so the liquid stays in. Discard the bottle. The label carries the same 15 minutes to 1 hour window and the same directions and warnings as the solid suppository, including 6 and over with under 6 sent to a doctor.

Who it suits: people who find a solid suppository awkward, anyone with limited hand dexterity, and caregivers. What owners report: the tip can feel firmer than expected, so a slow insertion matters; and the small volume means little leakage compared with an enema. It is not an enema. The liquid glycerin field is ranked in the best liquid glycerin suppositories.

Hemorrhoidal suppositories: coating, not producing

A hemorrhoidal suppository is not meant to produce a bowel movement; it is a protectant and, in the Preparation H formula, a vasoconstrictor that melts and coats swollen internal tissue. The Preparation H Suppositories Drug Facts label lists cocoa butter as a protectant and phenylephrine as a vasoconstrictor; its uses are temporary relief of itching, burning and discomfort of hemorrhoids and temporary shrinking of hemorrhoidal tissue. Directions: adults, insert one suppository rectally up to 4 times daily, especially at night, in the morning, or after each bowel movement; children under 12, ask a doctor.

Because the base is cocoa butter, these melt at close to body temperature and will leak; the label's timing (night, morning, after a bowel movement) is designed around that, and owners keep them refrigerated so they are firm enough to insert. Stop lines on the label: if bleeding occurs, or the condition worsens or does not improve within 7 days, stop use and ask a doctor. Which hemorrhoidal suppository to buy is in the best hemorrhoid suppositories.

Acetaminophen suppositories for a child with fever

FeverAll acetaminophen suppositories exist for one situation: a child who cannot keep oral medicine down. The rectal lining absorbs acetaminophen into the bloodstream, which is why these are dosed by age like any fever reducer. The FeverAll infant strength is 80 mg and its label covers ages 6 to 36 months, sending infants under 6 months to a doctor; the children's strength is 120 mg, labeled for ages 3 to 6; the junior strength is 325 mg, labeled for ages 6 to 12. The box prints the dosing interval and the daily maximum for each age, and that box, not this page, is the dose. Insertion is the standard routine at pediatric depth, about half an inch, holding the buttocks together afterward because a small child will push reflexively.

The label's stop lines: stop use and ask a doctor if fever gets worse or lasts more than 3 days, if pain gets worse or lasts more than 5 days, or if new symptoms appear, and acetaminophen carries a liver warning about combining products. The American Academy of Pediatrics says any fever in an infant under 3 months is a reason to call the doctor before giving anything at all. The pediatrician decides. Strengths and ages are compared in the best acetaminophen suppositories.

The shared rule under every type: the label sets the dose, the age line and the stop line. This page shows the hand skills; it does not change a single number the box prints.

How to use a liquid glycerin suppository (pre-filled applicator)

  1. 1

    Wash your hands and remove the cap

    Wash your hands. Remove the protective cap from the pre-filled applicator; the tip is already lubricated, so no additional lubricant is needed.

  2. 2

    Lie on your side

    Lie on your left side with your lower leg straight and your upper knee bent toward your chest.

  3. 3

    Insert the tip gently

    With the bottle angled slightly toward your back, gently insert the applicator tip into the rectum. Stop if you meet resistance.

  4. 4

    Squeeze and withdraw

    Squeeze the bottle until it is nearly empty, then withdraw the tip while still squeezing so the liquid stays inside. Discard the bottle.

  5. 5

    Stay lying down and wait for the label's window

    Remain lying down for several minutes. The Drug Facts label states a bowel movement generally follows in 15 minutes to 1 hour. Use once daily at most; if there is no bowel movement or any rectal bleeding, stop and ask a doctor.

Ready to buy? Start with our top picks

Whatever this guide steered you toward, here's where most readers land, ranked on verified label facts and value. Live price check on each.

Fleet Glycerin, Adult 50 ct

Best Overall

Fleet Glycerin, Adult 50 ct

glycerin · 50 ct · ~$4

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Dulcolax Bisacodyl 10 mg

Best Fast-Acting

Dulcolax Bisacodyl 10 mg

bisacodyl · 4 ct · ~$5

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Preparation H Suppositories

Best for Hemorrhoids

Preparation H Suppositories

12 ct x 2 · ~$18

Check Price
pH-D Boric Acid 600 mg

Best Boric Acid

pH-D Boric Acid 600 mg

600 mg · 24 ct · ~$27

Check Price
Pedia-Lax Liquid Glycerin, Kids

Best for Kids

Pedia-Lax Liquid Glycerin, Kids

ages 2 to 5 · 6 ct x 3 · ~$21

Check Price
FeverAll Infant 80 mg

Best Fever

FeverAll Infant 80 mg

acetaminophen · 6 ct · ~$13

Check Price

As an Amazon Associate we earn from qualifying purchases, at no cost to you.

Key terms

Hyperosmotic
Glycerin's mechanism: it draws water into the lower bowel, softening stool and prompting a movement. Non-stimulant, which is why glycerin is the first suppository most labels and pharmacists point to.
Stimulant laxative
Bisacodyl's mechanism: it acts on the bowel wall to trigger movement. Labels list cramps and rectal burning as possible effects and direct occasional use.
Pre-filled applicator
The liquid glycerin format: a single-use squeeze bottle with a lubricated tip. Same glycerin, same label window, no solid to handle.
Protectant
A hemorrhoidal label category for ingredients such as cocoa butter and zinc oxide that coat tissue to relieve irritation. Preparation H pairs a protectant with phenylephrine, a vasoconstrictor.
Single daily dose
The direction on every glycerin and bisacodyl suppository label: one suppository (or one half, where the label prints it) once daily, for occasional constipation, not beyond 1 week without a doctor.

Questions, answered

How do you use a glycerin suppository?

Chill it if soft, unwrap it, moisten the pointed end with water, lie on your left side with the upper knee bent, insert it pointed end first about 1 inch until it passes the muscle, squeeze your buttocks together briefly, and stay lying down about 15 minutes. The Fleet label states a bowel movement generally follows in 15 minutes to 1 hour; directions are one suppository once daily for ages 6 and over, with under 6 sent to a doctor.

How long do you hold a rectal suppository in?

As long as the urge allows, and at least about 15 minutes lying down so the base melts or dissolves. For a laxative, the label window is 15 minutes to 1 hour, and owners report a more complete result when the suppository has had most of that time. A hemorrhoidal suppository is meant to stay and melt; it is not held against an urge because it does not create one.

Can you use a rectal suppository every day?

Not a laxative suppository, not without a doctor: every glycerin and bisacodyl label says do not use laxative products for more than 1 week unless directed by a doctor, and the labeled use is occasional constipation. Hemorrhoidal suppositories are directed up to 4 times daily but capped at 7 days without a doctor. If you find you need a laxative suppository regularly, that is the label's signal to ask a clinician why.

What is the difference between a glycerin and a bisacodyl suppository?

Glycerin is hyperosmotic and draws water into the bowel; bisacodyl is a stimulant that acts on the bowel wall. Both labels state 15 minutes to 1 hour to a bowel movement. Bisacodyl's label lists cramps, faintness and rectal burning as possible effects and directs occasional use; glycerin does not carry those lines. Glycerin first, bisacodyl if glycerin has not worked and a doctor is fine with a stimulant, is the order the labels imply.

How do you use a liquid glycerin suppository?

Remove the cap, lie on your side, gently insert the pre-lubricated tip with the bottle angled slightly toward your back, squeeze until nearly empty, and withdraw while still squeezing. Stay lying down for several minutes. The Fleet Liquid Glycerin label carries the same 15 minutes to 1 hour window and the same 6-and-over direction as the solid suppository. It is a suppository in liquid form, not an enema.

Should hemorrhoid suppositories be refrigerated?

The Preparation H label permits refrigeration, and owners consistently store them cold because the cocoa butter base softens near body temperature and a firm suppository inserts far more easily. Use them as the label directs, up to 4 times daily, especially at night, in the morning or after a bowel movement, and stop and ask a doctor if bleeding occurs or symptoms last beyond 7 days.

Can I give my child a rectal suppository for fever?

Only after the pediatrician has said so. FeverAll acetaminophen suppositories are dosed by age on the box: infant 80 mg is labeled 6 to 36 months and sends under 6 months to a doctor; children's 120 mg is labeled 3 to 6 years; junior 325 mg is labeled 6 to 12 years. The label says to stop and ask a doctor if fever lasts more than 3 days. The AAP says any fever in an infant under 3 months is a call to the doctor before giving anything.