Our Pick: NOW Foods
Check price on Amazon →Best D-Mannose Supplements (2026): NOW, AZO, Nutricost and Zazzee Compared
D-mannose is a simple sugar sold as a supplement to support a healthy urinary tract, and the shelf divides into printed-dose capsules, unflavored powder, and a pharmacy brand that prints a claim instead of a milligram figure. NOW D-Mannose 500 mg (120 for $16.76) is the pick; NOW's 300 count is the bulk buy; Nutricost and Zazzee state 1,000 mg per serving; AZO is the pharmacy name. None treats or prevents a UTI. Prices verified via the Amazon Creators API on September 5, 2026.
By The Women's Health Desk2026-09-05~10 min read Ranked on verified label facts, never box claimsHow we research
Best OverallNOW Foods D-Mannose 500 mg, Non-GMO Project Verified, 120 Veg Capsules
NOW Foods · 4.6
$16.76
Buy NOW D-Mannose 500 mg, 120 Veg Capsules, at $16.76 (verified via the Amazon Creators API on September 5, 2026), about $0.14 per capsule ($16.76 divided by 120). It prints the dose, it prints the count, it is Non-GMO Project Verified per its title, and its label makes exactly one claim, the structure/function one every product here shares: supports a healthy urinary tract. If you take it regularly, the 300 count at $36.10 brings that to about $0.12 per capsule.
What D-mannose is and is not. It is a simple sugar related to glucose, sold as a dietary supplement in capsules and powder, and its labels are limited to supporting urinary tract health. It is not an antibiotic, it does not treat a urinary tract infection, and no product on this page claims it prevents one. Painful urination, blood in the urine, fever, chills or back pain are a clinician's problem the same day, not a supplement's. What can be compared across bottles is what the title prints: milligrams per capsule or per serving, count, powder versus capsule, and the price per capsule or serving.
We are a research and verification desk: we read the Supplement Facts panel, confirm the live listing and price through the Creators API, and weigh consistent owner reports about capsule size, powder taste and value. We do not use these products ourselves and we make no medical claims. Pick slots go to established brands; no brand paid for a placement. If you buy through our links we may earn an Amazon commission at no extra cost to you.
The short version
- Our pick is NOW D-Mannose 500 mg, 120 veg capsules, at $16.76 on September 5, 2026 (about $0.14 per capsule): printed dose, printed count, Non-GMO Project Verified.
- Bulk: NOW 500 mg, 300 capsules, $36.10 (about $0.12 each). Higher per-serving dose: Nutricost 1,000 mg per serving, 120 capsules for $14.95; Zazzee 1,000 mg per serving, 180 capsules for $24.97.
- AZO D-Mannose (120 for $29.49) is the pharmacy brand; its title says clinical strength and does not state milligrams, so we print none.
- Powder (NOW, 6 oz, $27.98) suits people who want to measure their own serving and dislike capsules.
- Every product is a supplement that supports urinary tract health. None treats or prevents a UTI; painful urination, blood, fever or back pain means see a clinician today.
At a glance
| Product | Form | Dose (per title) | Count | Per capsule / serving | Price (9/5/26) | Check price |
|---|---|---|---|---|---|---|
| NOW D-Mannose, 120 ct | Veg capsule | 500 mg | 120 | About $0.14 per capsule | $16.76 | Check price on Amazon |
| NOW D-Mannose, 300 ct | Capsule | 500 mg | 300 | About $0.12 per capsule | $36.10 | Check price on Amazon |
| Nutricost D-Mannose | Capsule | 1,000 mg per serving | 120 (60 servings) | About $0.25 per serving | $14.95 | Check price on Amazon |
| Zazzee D-Mannose | Vegan capsule | 1000 mg per serving | 180 | About $0.14 per capsule | $24.97 | Check price on Amazon |
| AZO D-Mannose, Clinical Strength | Capsule | Not published (clinical strength) | 120 | About $0.25 per capsule | $29.49 | Check price on Amazon |
| NOW D-Mannose Powder | Powder | Not published in title | 6 oz | Not computed | $27.98 | Check price on Amazon |
The D-mannose field. Dose appears only where the Amazon listing title states it. Cost per capsule is computed where the title states a capsule count; per serving where the title states servings. Prices verified via the Creators API on September 5, 2026.
NOW Foods D-Mannose 500 mg, Non-GMO Project Verified, 120 Veg Capsules
NOW Foods
Printed 500 mg, printed 120 count, Non-GMO Project Verified, about $0.14 per capsule.
Our verdict: NOW's 500 mg capsule is the reference D-mannose product: the dose is printed, the count is printed, the Non-GMO verification is on the title, and the claim is the single structure/function line the whole category shares. At $16.76 for 120 it is about $0.14 per capsule. NOW has been a supplement manufacturer for decades and owner reports are as consistent as any on the shelf.
Verified: D-Mannose 500 mg per veg capsule, 120 count, Non-GMO Project Verified per the listing title, a dietary supplement labeled to support a healthy urinary tract. Live at $16.76 on Amazon, verified via the Creators API on September 5, 2026.
Everything printed. NOW D-Mannose 500 mg states its dose, its count, and its Non-GMO Project verification on the listing. The label's claim is that it supports a healthy urinary tract, with the supplement asterisk, and nothing more. It does not treat or prevent a UTI.
NOW also sells the same 500 mg capsule in a 300 count and as an unflavored powder, both below. Owners who pair D-mannose with a cranberry supplement will find that shelf ranked in the best cranberry pills.
Who should buy it
Buy NOW D-Mannose 500 mg if you want a printed dose and count from an established manufacturer at a low per-capsule price, and you understand it supports urinary tract health and treats nothing.
What we don't like
A 500 mg capsule means people following a label serving larger than that take several capsules, which the 1,000 mg per serving products below address.
- Active ingredient
- D-Mannose (dietary supplement)
- Strength
- 500 mg per capsule
- Count
- 120 veg capsules
- Form
- Oral capsule
- Label ages
- Adults; consult a doctor if pregnant, nursing or diabetic
- Cost per capsule
- About $0.14 ($16.76 divided by 120)
- Packaging
- 120 count bottle
What we like
- Printed 500 mg dose and 120 count
- Non-GMO Project Verified per the title
- About $0.14 per capsule from a long-established maker
Worth noting
- 500 mg per capsule means multiple capsules per larger serving
NOW D-Mannose 500 mg, 300 Capsules, Vegan, Non-GMO
NOW Foods
The same 500 mg capsule by the 300, about $0.12 each.
Our verdict: Same capsule, bigger bottle: $36.10 divided by 300 is about $0.12 per capsule, the lowest per-capsule figure on the page. For anyone who takes D-mannose regularly as the label directs, this is the bottle to buy after the 120 count has proven it suits them.
Verified: D-Mannose 500 mg per capsule, 300 count, vegan and non-GMO per the listing title. Live at $36.10 on Amazon, verified via the Creators API on September 5, 2026.
The repeat-buyer bottle. NOW D-Mannose 500 mg, 300 capsules is the identical printed-dose capsule in a bottle two and a half times the size. Vegan and non-GMO per the title. The claim is unchanged: supports a healthy urinary tract.
Buy the 120 count first if you have never used D-mannose. Bulk bottles of any supplement want a cool, dry cabinet; the same storage rules apply as for every product on the site.
Who should buy it
Buy the 300 count if NOW D-Mannose already suits you and you take it regularly enough to use 300 capsules before the expiry on the bottle.
What we don't like
A big bottle for a first purchase, and the same 500 mg per capsule as the smaller size.
- Active ingredient
- D-Mannose (dietary supplement)
- Strength
- 500 mg per capsule
- Count
- 300 capsules
- Form
- Oral capsule
- Label ages
- Adults; consult a doctor if pregnant, nursing or diabetic
- Cost per capsule
- About $0.12 ($36.10 divided by 300)
- Packaging
- 300 count bottle
What we like
- About $0.12 per capsule, lowest on the page
- Identical printed 500 mg dose
- Vegan, non-GMO per the title
Worth noting
- Not a first-purchase size
Nutricost D-Mannose 1,000 mg Per Serving, 120 Capsules, 60 Servings
Nutricost
A printed 1,000 mg per serving in 60 two-capsule servings for $14.95, about $0.25 a serving.
Our verdict: Nutricost prints the arithmetic on its title: 1,000 mg per serving, 120 capsules, 60 servings, which works out to two 500 mg capsules per serving. At $14.95 that is about $0.25 per serving ($14.95 divided by 60), or about $0.12 per capsule ($14.95 divided by 120), matching NOW's bulk price in a smaller bottle. Nutricost is the value brand with a real record; owner reports are steady.
Verified: D-Mannose 1,000 mg per serving, 120 capsules, 60 servings per the listing title, a dietary supplement. Live at $14.95 on Amazon, verified via the Creators API on September 5, 2026.
The title does the math for you. Nutricost D-Mannose states 1,000 mg per serving, 120 capsules and 60 servings, so a serving is two capsules. It is a dietary supplement labeled to support urinary tract health and it treats nothing.
Nutricost also sells cranberry extract for the buyer who wants both, ranked in the best cranberry pills, and boric acid suppositories, a vaginal product with every boric acid warning that belongs to the boric acid shelf, not this one.
Who should buy it
Buy Nutricost if you want a printed 1,000 mg per serving at the lowest per-capsule price in a bottle smaller than NOW's bulk size.
What we don't like
A value brand's packaging and a smaller owner record than NOW, and a two-capsule serving that some would rather take as one.
- Active ingredient
- D-Mannose (dietary supplement)
- Strength
- 1,000 mg per serving (two capsules)
- Count
- 120 capsules, 60 servings
- Form
- Oral capsule
- Label ages
- Adults; consult a doctor if pregnant, nursing or diabetic
- Cost per serving
- About $0.25 ($14.95 divided by 60)
- Packaging
- 120 count bottle
What we like
- Printed 1,000 mg per serving and 60 servings
- About $0.12 per capsule
- Established value brand
Worth noting
- Two capsules per serving
- Smaller owner record than NOW
Zazzee D-Mannose, 1000 mg Per Serving, 180 Vegan Capsules, 3 Month Supply
Zazzee
Printed 1000 mg per serving, 180 vegan capsules framed as three months, $24.97.
Our verdict: Zazzee frames its bottle by the month: 1000 mg per serving, 180 vegan capsules, a three-month supply, which implies two capsules a day. At $24.97 that is about $0.14 per capsule ($24.97 divided by 180). It is an Amazon-native brand with a good record on this shelf, and the vegan capsule and monthly framing are its differences from Nutricost.
Verified: D-Mannose 1000 mg per serving, 180 vegan capsules, 3 month supply per the listing title, a dietary supplement. Live at $24.97 on Amazon, verified via the Creators API on September 5, 2026.
Framed by the month. Zazzee D-Mannose states 1000 mg per serving, 180 vegan capsules and a 3 month supply on its title, which works out to two capsules per day at the label serving. It supports urinary tract health as a supplement; it treats nothing.
Zazzee also makes an organic cranberry 25:1 extract for buyers who want both on one order, ranked in the best cranberry pills.
Who should buy it
Buy Zazzee if you want a printed 1000 mg serving in a vegan capsule and like a bottle sized to a three-month routine.
What we don't like
An Amazon-native brand with a shorter record than NOW, and a monthly framing that assumes the label serving every day.
- Active ingredient
- D-Mannose (dietary supplement)
- Strength
- 1000 mg per serving
- Count
- 180 vegan capsules (3 month supply per title)
- Form
- Oral capsule
- Label ages
- Adults; consult a doctor if pregnant, nursing or diabetic
- Cost per capsule
- About $0.14 ($24.97 divided by 180)
- Packaging
- 180 count bottle
What we like
- Printed 1000 mg serving, vegan capsule
- About $0.14 per capsule
- Three-month framing on the title
Worth noting
- Shorter brand record than NOW
AZO D-Mannose Supplement for Women and Men, Clinical Strength, 120 Capsules
AZO
The pharmacy name in D-mannose, 120 capsules for $29.49; the title says clinical strength, not milligrams.
Our verdict: AZO is the brand people already know from the urinary aisle, and its D-mannose is the one most likely to be in a drugstore. The listing prints 120 capsules and the phrase clinical strength; it does not print milligrams, so we do not. At $29.49 it is about $0.25 per capsule ($29.49 divided by 120), the highest per-capsule price here, which is the cost of the brand.
Verified: D-Mannose capsules, 120 count, labeled clinical strength on the listing title; milligrams not published in the title. Live at $29.49 on Amazon, verified via the Creators API on September 5, 2026.
A phrase where a number should be. AZO D-Mannose describes itself as clinical strength on the listing title and states 120 capsules. It does not state milligrams per capsule in the title, and this page prints only what the title states. The label's claim is urinary tract support; it treats nothing.
AZO's urinary shelf also includes Pro Strength cranberry, which does print 600 mg on its title, and its daily vaginal probiotic, ranked in the best vaginal probiotics.
Who should buy it
Buy AZO D-Mannose if the pharmacy brand matters to you and you accept a marketing phrase in place of a printed milligram figure.
What we don't like
No milligrams in the title, the highest per-capsule price on the page, and clinical strength as a descriptor that a supplement label cannot back with an approved claim.
- Active ingredient
- D-Mannose (dietary supplement)
- Strength
- Not published in the listing title (clinical strength)
- Count
- 120 capsules
- Form
- Oral capsule
- Label ages
- Adults; consult a doctor if pregnant, nursing or diabetic
- Cost per capsule
- About $0.25 ($29.49 divided by 120)
- Packaging
- 120 count bottle
What we like
- Widest pharmacy distribution
- Printed 120 count
Worth noting
- Milligrams not stated in the title
- About $0.25 per capsule
NOW Foods D-Mannose Powder, Non-GMO Project Verified, 6 Ounce
NOW Foods
Unflavored, Non-GMO Project Verified powder for people who would rather measure than swallow, 6 oz for $27.98.
Our verdict: The powder is for people who dislike capsules or want to measure the serving the label directs with a scoop. NOW's is Non-GMO Project Verified per the title, unflavored, and owners describe it as mildly sweet and easy to dissolve in water. The title states 6 oz and no per-serving milligrams, so we compute nothing per serving; the label on the container does the measuring.
Verified: D-Mannose powder, Non-GMO Project Verified per the listing title, 6 ounce container, a dietary supplement. Live at $27.98 on Amazon, verified via the Creators API on September 5, 2026.
Measure, do not swallow. NOW D-Mannose Powder is the same supplement in a 6 oz container of loose powder with a scoop, Non-GMO Project Verified per the listing. The claim is urinary tract support; it treats nothing. The title does not state milligrams per scoop, and the container's label is where the serving is defined.
At $27.98 (verified September 5, 2026) for 6 oz we compute no per-serving cost because the title does not state servings. The capsule versions above are the simpler buy for most people.
Who should buy it
Buy the powder if you cannot or would rather not swallow capsules, or you want to measure the label serving yourself.
What we don't like
No servings stated on the title, so no per-serving math, and the mess and measuring of any loose powder.
- Active ingredient
- D-Mannose (dietary supplement)
- Strength
- Not published in the listing title (per-scoop serving on the container label)
- Count
- 6 oz
- Form
- Powder with scoop
- Label ages
- Adults; consult a doctor if pregnant, nursing or diabetic
- Cost per serving
- Not computed (servings not published in title)
- Packaging
- 6 oz container
What we like
- Capsule-free format, Non-GMO Project Verified
- Dissolves cleanly per owners
Worth noting
- Servings not on the title
- Measuring and mess
What you'll need
The six things that go with a vaginal suppository: applicators, pH strips so you know what you are treating, a probiotic and a vitamin E option, a moisturizer, and a gentle wash. See a clinician for diagnosis. Prices are approximate at time of writing.
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Quick shop: every pick
Skip the scroll: the whole lineup, with a live price check on each.
- NOW Foods D-Mannose 500 mg, Non-GMO Project Verified, 120 Veg CapsulesBest D-Mannose Supplement OverallNOW Foods · $16.76Check price on Amazon
- NOW D-Mannose 500 mg, 300 Capsules, Vegan, Non-GMOBest Bulk D-MannoseNOW Foods · $36.10Check price on Amazon
- Nutricost D-Mannose 1,000 mg Per Serving, 120 Capsules, 60 ServingsBest Value 1,000 mg ServingNutricost · $14.95Check price on Amazon
- Zazzee D-Mannose, 1000 mg Per Serving, 180 Vegan Capsules, 3 Month SupplyBest Three-Month BottleZazzee · $24.97Check price on Amazon
- AZO D-Mannose Supplement for Women and Men, Clinical Strength, 120 CapsulesBest Pharmacy-Brand D-MannoseAZO · $29.49Check price on Amazon
- NOW Foods D-Mannose Powder, Non-GMO Project Verified, 6 OunceBest D-Mannose PowderNOW Foods · $27.98Check price on Amazon
How we chose
Each product was checked the same way: live listing and price confirmed through the Amazon Creators API on September 5, 2026; dose, count and servings taken only from the listing title, with "not published" wherever the title is silent; the brand's label read for its use statement; and owner reports weighed for capsule size, powder solubility and taste, and value over months. Pick slots go to established brands. We do not use these products ourselves and we claim no clinical outcome. Per-capsule and per-serving costs are arithmetic on the printed count, nothing more.
Compliance for this shelf. D-mannose is a dietary supplement. It is not approved to treat, cure or prevent urinary tract infections or any other condition, and this page uses structure/function language only: supports a healthy urinary tract. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant or nursing, or have diabetes, the labels say to consult a doctor before use; painful urination, blood in the urine, fever, chills or back pain are reasons to see a clinician the same day.
Questions, answered
What is the best D-mannose supplement?
Our pick is NOW D-Mannose 500 mg, 120 veg capsules, at $16.76 on September 5, 2026 (about $0.14 per capsule), for its printed dose and count, Non-GMO Project verification and long manufacturer record. NOW's 300 count at $36.10 is the bulk buy at about $0.12 per capsule. Nutricost ($14.95) and Zazzee ($24.97) print 1,000 mg per serving. AZO ($29.49 for 120) is the pharmacy brand and does not print milligrams. All are supplements that support urinary tract health; none treats a UTI.
Does D-mannose treat or prevent UTIs?
No product on this page claims that, and neither do we. D-mannose is a dietary supplement whose labels say it supports a healthy urinary tract. A urinary tract infection is diagnosed and treated by a clinician, and symptoms like burning, urgency, blood in the urine, fever, chills or back pain are reasons to see one the same day.
How much D-mannose is in a capsule?
What the title states: NOW capsules are 500 mg each; Nutricost and Zazzee state 1,000 mg per serving, which on Nutricost's title is two capsules; AZO states clinical strength and no milligrams; NOW powder states 6 oz and defines the scoop serving on the container label. Follow your bottle's own directions.
Capsule or powder?
Capsules are simpler and the printed dose makes cost comparison easy. Powder suits people who cannot swallow capsules or who want to measure the label serving with a scoop; owners describe NOW's as mildly sweet and easy to dissolve. Same supplement, same claim.
Can I take D-mannose if I have diabetes?
D-mannose is a sugar, and the labels say to consult a doctor before use if you have diabetes. Ask first.
Can I take D-mannose with cranberry or a probiotic?
Owners commonly describe combining them, and some products bundle cranberry with a probiotic. All are supplements with support claims; combining them is a routine, not a treatment, and it does not change what any of them is approved to do. Cranberry pills and vaginal probiotics are ranked on their own pages.
Which D-mannose is cheapest per capsule?
On September 5, 2026: NOW 300 count at about $0.12 per capsule ($36.10 divided by 300); Nutricost at about $0.12 per capsule ($14.95 divided by 120, or about $0.25 per 1,000 mg serving); NOW 120 count and Zazzee at about $0.14 per capsule; AZO at about $0.25 per capsule ($29.49 divided by 120). NOW powder does not state servings on its title, so we compute nothing for it.
Filed under Buyer's Guide
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